Toda M - Search Results

1

Orally active PDE4 inhibitors with therapeutic potential.

Ochiai H, Ohtani T, Ishida A, Kishikawa K, Obata T, Nakai H, Toda M. Ochiai H, et al. Among authors: toda m. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1323-7. doi: 10.1016/j.bmcl.2003.12.018. Bioorg Med Chem Lett. 2004. PMID: 14980691

2

Design and synthesis of a selective EP4-receptor agonist. Part 2: 3,7-dithiaPGE1 derivatives with high selectivity.

Maruyama T, Asada M, Shiraishi T, Ishida A, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: toda m. Bioorg Med Chem. 2002 Apr;10(4):989-1008. doi: 10.1016/s0968-0896(01)00352-2. Bioorg Med Chem. 2002. PMID: 11836108

3

Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.

Tani K, Naganawa A, Ishida A, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: toda m. Bioorg Med Chem. 2002 Apr;10(4):1093-106. doi: 10.1016/s0968-0896(01)00369-8. Bioorg Med Chem. 2002. PMID: 11836120

4

Development of a highly selective EP2-receptor agonist. Part 2: identification of 16-hydroxy-17,17-trimethylene 9beta-chloro PGF derivatives.

Tani K, Naganawa A, Ishida A, Egashira H, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: toda m. Bioorg Med Chem. 2002 Apr;10(4):1107-14. doi: 10.1016/s0968-0896(01)00370-4. Bioorg Med Chem. 2002. PMID: 11836121

5

Highly potent inhibitors of TNF-alpha production. Part 1: Discovery of chemical leads.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: toda m. Bioorg Med Chem Lett. 2002 Mar 25;12(6):903-5. doi: 10.1016/s0960-894x(02)00036-7. Bioorg Med Chem Lett. 2002. PMID: 11958990

6

Highly potent inhibitors of TNF-alpha production. Part I: discovery of new chemical leads and their structure-activity relationships.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Terai K, Kamoshima W, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: toda m. Bioorg Med Chem. 2002 Dec;10(12):3757-86. doi: 10.1016/s0968-0896(02)00381-4. Bioorg Med Chem. 2002. PMID: 12413832

7

Highly potent inhibitors of TNF-alpha production. Part II: metabolic stabilization of a newly found chemical lead and conformational analysis of an active diastereoisomer.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: toda m. Bioorg Med Chem. 2002 Dec;10(12):3787-805. doi: 10.1016/s0968-0896(02)00380-2. Bioorg Med Chem. 2002. PMID: 12413833

8

Synthesis, further biological evaluation and pharmacodynamics of newly discovered inhibitors of TNF-alpha production.

Matsui T, Kondo T, Nakatani S, Omawari N, Sakai M, Mori H, Ogata A, Kato J, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Among authors: toda m. Bioorg Med Chem. 2003 Sep 1;11(18):3937-43. doi: 10.1016/s0968-0896(03)00409-7. Bioorg Med Chem. 2003. PMID: 12927854

9

New orally active PDE4 inhibitors with therapeutic potential.

Ochiai H, Ishida A, Ohtani T, Kusumi K, Kishikawa K, Obata T, Nakai H, Toda M. Ochiai H, et al. Among authors: toda m. Bioorg Med Chem Lett. 2004 Jan 5;14(1):29-32. doi: 10.1016/j.bmcl.2003.10.025. Bioorg Med Chem Lett. 2004. PMID: 14684291

10

Highly potent PDE4 inhibitors with therapeutic potential.

Ochiai H, Ohtani T, Ishida A, Kusumi K, Kato M, Kohno H, Kishikawa K, Obata T, Nakai H, Toda M. Ochiai H, et al. Among authors: toda m. Bioorg Med Chem Lett. 2004 Jan 5;14(1):207-10. doi: 10.1016/j.bmcl.2003.09.087. Bioorg Med Chem Lett. 2004. PMID: 14684329

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