LeCluyse EL - Search Results

1

Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers.

Faucette SR, Wang H, Hamilton GA, Jolley SL, Gilbert D, Lindley C, Yan B, Negishi M, LeCluyse EL. Faucette SR, et al. Among authors: lecluyse el. Drug Metab Dispos. 2004 Mar;32(3):348-58. doi: 10.1124/dmd.32.3.348. Drug Metab Dispos. 2004. PMID: 14977870

2

Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.

Wang H, Faucette S, Moore R, Sueyoshi T, Negishi M, LeCluyse E. Wang H, et al. J Biol Chem. 2004 Jul 9;279(28):29295-301. doi: 10.1074/jbc.M400580200. Epub 2004 Apr 28. J Biol Chem. 2004. PMID: 15123723 Free article.

3

The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes.

Lindley C, Hamilton G, McCune JS, Faucette S, Shord SS, Hawke RL, Wang H, Gilbert D, Jolley S, Yan B, LeCluyse EL. Lindley C, et al. Among authors: lecluyse el. Drug Metab Dispos. 2002 Jul;30(7):814-22. doi: 10.1124/dmd.30.7.814. Drug Metab Dispos. 2002. PMID: 12065440

4

A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.

Wang H, Faucette S, Sueyoshi T, Moore R, Ferguson S, Negishi M, LeCluyse EL. Wang H, et al. Among authors: lecluyse el. J Biol Chem. 2003 Apr 18;278(16):14146-52. doi: 10.1074/jbc.M212482200. Epub 2003 Feb 5. J Biol Chem. 2003. PMID: 12571232 Free article.

5

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition.

Sahi J, Black CB, Hamilton GA, Zheng X, Jolley S, Rose KA, Gilbert D, LeCluyse EL, Sinz MW. Sahi J, et al. Among authors: lecluyse el. Drug Metab Dispos. 2003 Apr;31(4):439-46. doi: 10.1124/dmd.31.4.439. Drug Metab Dispos. 2003. PMID: 12642470

6

Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.

Wang H, Faucette SR, Gilbert D, Jolley SL, Sueyoshi T, Negishi M, LeCluyse EL. Wang H, et al. Among authors: lecluyse el. Drug Metab Dispos. 2003 May;31(5):620-30. doi: 10.1124/dmd.31.5.620. Drug Metab Dispos. 2003. PMID: 12695351

7

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

Wang H, LeCluyse EL. Wang H, et al. Among authors: lecluyse el. Clin Pharmacokinet. 2003;42(15):1331-57. doi: 10.2165/00003088-200342150-00003. Clin Pharmacokinet. 2003. PMID: 14674787 Review.

8

Isolation and culture of primary human hepatocytes.

LeCluyse EL, Alexandre E, Hamilton GA, Viollon-Abadie C, Coon DJ, Jolley S, Richert L. LeCluyse EL, et al. Methods Mol Biol. 2005;290:207-29. doi: 10.1385/1-59259-838-2:207. Methods Mol Biol. 2005. PMID: 15361665

9

Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers.

Smith CM, Faucette SR, Wang H, LeCluyse EL. Smith CM, et al. Among authors: lecluyse el. J Biochem Mol Toxicol. 2005;19(2):96-108. doi: 10.1002/jbt.20058. J Biochem Mol Toxicol. 2005. PMID: 15849716

10

Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.

Smith CM, Graham RA, Krol WL, Silver IS, Negishi M, Wang H, Lecluyse EL. Smith CM, et al. Among authors: lecluyse el. J Pharmacol Exp Ther. 2005 Dec;315(3):1256-64. doi: 10.1124/jpet.105.090795. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135700

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