Molkentin JD - Search Results

1

PKC-alpha regulates cardiac contractility and propensity toward heart failure.

Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. Braz JC, et al. Among authors: molkentin jd. Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966518 Free article.

2

Prevention of cardiac hypertrophy in mice by calcineurin inhibition.

Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Sussman MA, et al. Among authors: molkentin jd. Science. 1998 Sep 11;281(5383):1690-3. doi: 10.1126/science.281.5383.1690. Science. 1998. PMID: 9733519

3

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure.

De Windt LJ, Lim HW, Taigen T, Wencker D, Condorelli G, Dorn GW 2nd, Kitsis RN, Molkentin JD. De Windt LJ, et al. Among authors: molkentin jd. Circ Res. 2000 Feb 18;86(3):255-63. doi: 10.1161/01.res.86.3.255. Circ Res. 2000. PMID: 10679475

4

Hypertrophic defect unmasked by calcineurin expression in asymptomatic tropomodulin overexpressing transgenic mice.

Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Witt SA, Kimball TR, Price R, Lim HW, Molkentin JD. Sussman MA, et al. Among authors: molkentin jd. Cardiovasc Res. 2000 Apr;46(1):90-101. doi: 10.1016/s0008-6363(99)00422-8. Cardiovasc Res. 2000. PMID: 10727657

5

Re-evaluating sarcoplasmic reticulum function in heart failure.

Delling U, Sussman MA, Molkentin JD. Delling U, et al. Among authors: molkentin jd. Nat Med. 2000 Sep;6(9):942-3. doi: 10.1038/79592. Nat Med. 2000. PMID: 10973288 No abstract available.

6

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice.

Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, Molkentin JD. Bueno OF, et al. Among authors: molkentin jd. EMBO J. 2000 Dec 1;19(23):6341-50. doi: 10.1093/emboj/19.23.6341. EMBO J. 2000. PMID: 11101507 Free PMC article.

7

Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo.

De Windt LJ, Lim HW, Bueno OF, Liang Q, Delling U, Braz JC, Glascock BJ, Kimball TF, del Monte F, Hajjar RJ, Molkentin JD. De Windt LJ, et al. Among authors: molkentin jd. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3322-7. doi: 10.1073/pnas.031371998. Proc Natl Acad Sci U S A. 2001. PMID: 11248077 Free PMC article.

8

Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK inactivation in cardiac myocytes.

Lim HW, New L, Han J, Molkentin JD. Lim HW, et al. Among authors: molkentin jd. J Biol Chem. 2001 May 11;276(19):15913-9. doi: 10.1074/jbc.M100452200. Epub 2001 Feb 22. J Biol Chem. 2001. PMID: 11279073 Free article.

9

Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy.

Aronow BJ, Toyokawa T, Canning A, Haghighi K, Delling U, Kranias E, Molkentin JD, Dorn GW 2nd. Aronow BJ, et al. Among authors: molkentin jd. Physiol Genomics. 2001 Jun 6;6(1):19-28. doi: 10.1152/physiolgenomics.2001.6.1.19. Physiol Genomics. 2001. PMID: 11395543

10

PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2).

Braz JC, Bueno OF, De Windt LJ, Molkentin JD. Braz JC, et al. Among authors: molkentin jd. J Cell Biol. 2002 Mar 4;156(5):905-19. doi: 10.1083/jcb.200108062. Epub 2002 Feb 25. J Cell Biol. 2002. PMID: 11864993 Free PMC article.

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