Dennis PA - Search Results

1

Targeting aberrant signal transduction pathways in lung cancer.

Gills JJ, Granville CA, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Cancer Biol Ther. 2004 Feb;3(2):147-55. doi: 10.4161/cbt.3.2.612. Epub 2004 Feb 1. Cancer Biol Ther. 2004. PMID: 14764993 Free article. Review.

2

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

Brognard J, Clark AS, Ni Y, Dennis PA. Brognard J, et al. Among authors: dennis pa. Cancer Res. 2001 May 15;61(10):3986-97. Cancer Res. 2001. PMID: 11358816

3

Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2.

Cuello M, Ettenberg SA, Clark AS, Keane MM, Posner RH, Nau MM, Dennis PA, Lipkowitz S. Cuello M, et al. Among authors: dennis pa. Cancer Res. 2001 Jun 15;61(12):4892-900. Cancer Res. 2001. PMID: 11406568

4

Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.

Clark AS, West K, Streicher S, Dennis PA. Clark AS, et al. Among authors: dennis pa. Mol Cancer Ther. 2002 Jul;1(9):707-17. Mol Cancer Ther. 2002. PMID: 12479367

5

Activation of the PI3K/Akt pathway and chemotherapeutic resistance.

West KA, Castillo SS, Dennis PA. West KA, et al. Among authors: dennis pa. Drug Resist Updat. 2002 Dec;5(6):234-48. doi: 10.1016/s1368-7646(02)00120-6. Drug Resist Updat. 2002. PMID: 12531180 Review.

6

Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCdelta promotes cellular survival and chemotherapeutic resistance.

Clark AS, West KA, Blumberg PM, Dennis PA. Clark AS, et al. Among authors: dennis pa. Cancer Res. 2003 Feb 15;63(4):780-6. Cancer Res. 2003. PMID: 12591726

7

Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo.

West KA, Linnoila IR, Belinsky SA, Harris CC, Dennis PA. West KA, et al. Among authors: dennis pa. Cancer Res. 2004 Jan 15;64(2):446-51. doi: 10.1158/0008-5472.can-03-3241. Cancer Res. 2004. PMID: 14744754

8

Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues.

Castillo SS, Brognard J, Petukhov PA, Zhang C, Tsurutani J, Granville CA, Li M, Jung M, West KA, Gills JG, Kozikowski AP, Dennis PA. Castillo SS, et al. Among authors: dennis pa. Cancer Res. 2004 Apr 15;64(8):2782-92. doi: 10.1158/0008-5472.can-03-1530. Cancer Res. 2004. PMID: 15087394

9

The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt.

Gills JJ, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Expert Opin Investig Drugs. 2004 Jul;13(7):787-97. doi: 10.1517/13543784.13.7.787. Expert Opin Investig Drugs. 2004. PMID: 15212619 Review.

10

An overview of lung cancer genomics and proteomics.

Granville CA, Dennis PA. Granville CA, et al. Among authors: dennis pa. Am J Respir Cell Mol Biol. 2005 Mar;32(3):169-76. doi: 10.1165/rcmb.F290. Am J Respir Cell Mol Biol. 2005. PMID: 15713815 Review.

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