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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells.
Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, Grewal N, Spiess PJ, Antony PA, Palmer DC, Tagaya Y, Rosenberg SA, Waldmann TA, Restifo NP. Klebanoff CA, et al. Among authors: rosenberg sa. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1969-74. doi: 10.1073/pnas.0307298101. Epub 2004 Feb 4. Proc Natl Acad Sci U S A. 2004. PMID: 14762166 Free PMC article.
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.
Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, Duray PH, Steinberg SM, Allison JP, Davis TA, Rosenberg SA. Phan GQ, et al. Among authors: rosenberg sa. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8372-7. doi: 10.1073/pnas.1533209100. Epub 2003 Jun 25. Proc Natl Acad Sci U S A. 2003. PMID: 12826605 Free PMC article. Clinical Trial.
Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.
Overwijk WW, Theoret MR, Finkelstein SE, Surman DR, de Jong LA, Vyth-Dreese FA, Dellemijn TA, Antony PA, Spiess PJ, Palmer DC, Heimann DM, Klebanoff CA, Yu Z, Hwang LN, Feigenbaum L, Kruisbeek AM, Rosenberg SA, Restifo NP. Overwijk WW, et al. Among authors: rosenberg sa. J Exp Med. 2003 Aug 18;198(4):569-80. doi: 10.1084/jem.20030590. J Exp Med. 2003. PMID: 12925674 Free PMC article.
High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens.
Morgan RA, Dudley ME, Yu YY, Zheng Z, Robbins PF, Theoret MR, Wunderlich JR, Hughes MS, Restifo NP, Rosenberg SA. Morgan RA, et al. Among authors: rosenberg sa. J Immunol. 2003 Sep 15;171(6):3287-95. doi: 10.4049/jimmunol.171.6.3287. J Immunol. 2003. PMID: 12960359 Free PMC article.
Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer.
Finkelstein SE, Heimann DM, Klebanoff CA, Antony PA, Gattinoni L, Hinrichs CS, Hwang LN, Palmer DC, Spiess PJ, Surman DR, Wrzesiniski C, Yu Z, Rosenberg SA, Restifo NP. Finkelstein SE, et al. Among authors: rosenberg sa. J Leukoc Biol. 2004 Aug;76(2):333-7. doi: 10.1189/jlb.0304120. Epub 2004 May 20. J Leukoc Biol. 2004. PMID: 15155774 Free PMC article.
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.
Antony PA, Piccirillo CA, Akpinarli A, Finkelstein SE, Speiss PJ, Surman DR, Palmer DC, Chan CC, Klebanoff CA, Overwijk WW, Rosenberg SA, Restifo NP. Antony PA, et al. Among authors: rosenberg sa. J Immunol. 2005 Mar 1;174(5):2591-601. doi: 10.4049/jimmunol.174.5.2591. J Immunol. 2005. PMID: 15728465 Free PMC article.
Bcl-2 overexpression enhances tumor-specific T-cell survival.
Charo J, Finkelstein SE, Grewal N, Restifo NP, Robbins PF, Rosenberg SA. Charo J, et al. Among authors: rosenberg sa. Cancer Res. 2005 Mar 1;65(5):2001-8. doi: 10.1158/0008-5472.CAN-04-2006. Cancer Res. 2005. PMID: 15753400 Free PMC article.
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.
Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, Palmer DC, Antony PA, Hwang ST, Rosenberg SA, Waldmann TA, Restifo NP. Klebanoff CA, et al. Among authors: rosenberg sa. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9571-6. doi: 10.1073/pnas.0503726102. Epub 2005 Jun 24. Proc Natl Acad Sci U S A. 2005. PMID: 15980149 Free PMC article.
1,359 results