Botros M - Search Results

1

A selective AT2 receptor ligand with a gamma-turn-like mimetic replacing the amino acid residues 4-5 of angiotensin II.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Karlén A, Hallberg A. Rosenström U, et al. Among authors: botros m. J Med Chem. 2004 Feb 12;47(4):859-70. doi: 10.1021/jm030921v. J Med Chem. 2004. PMID: 14761188

2

Synthesis and AT2 receptor-binding properties of angiotensin II analogues.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Hallberg A, Karlén A. Rosenström U, et al. Among authors: botros m. J Pept Res. 2004 Nov;64(5):194-201. doi: 10.1111/j.1399-3011.2004.00184.x. J Pept Res. 2004. PMID: 15485557

3

First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo.

Wan Y, Wallinder C, Johansson B, Holm M, Mahalingam AK, Wu X, Botros M, Karlén A, Pettersson A, Nyberg F, Fändriks L, Hallberg A, Alterman M. Wan Y, et al. Among authors: botros m. J Med Chem. 2004 Mar 11;47(6):1536-46. doi: 10.1021/jm031031i. J Med Chem. 2004. PMID: 14998339

4

New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.

Rosenström U, Sköld C, Plouffe B, Beaudry H, Lindeberg G, Botros M, Nyberg F, Wolf G, Karlén A, Gallo-Payet N, Hallberg A. Rosenström U, et al. Among authors: botros m. J Med Chem. 2005 Jun 16;48(12):4009-24. doi: 10.1021/jm0491492. J Med Chem. 2005. PMID: 15943474

5

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity.

Georgsson J, Sköld C, Plouffe B, Lindeberg G, Botros M, Larhed M, Nyberg F, Gallo-Payet N, Gogoll A, Karlén A, Hallberg A. Georgsson J, et al. Among authors: botros m. J Med Chem. 2005 Oct 20;48(21):6620-31. doi: 10.1021/jm050280z. J Med Chem. 2005. PMID: 16220978

6

Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity.

Georgsson J, Rosenström U, Wallinder C, Beaudry H, Plouffe B, Lindeberg G, Botros M, Nyberg F, Karlén A, Gallo-Payet N, Hallberg A. Georgsson J, et al. Among authors: botros m. Bioorg Med Chem. 2006 Sep 1;14(17):5963-72. doi: 10.1016/j.bmc.2006.05.019. Epub 2006 Jun 5. Bioorg Med Chem. 2006. PMID: 16753301

7

Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors.

Rosenström U, Sköld C, Lindeberg G, Botros M, Nyberg F, Karlén A, Hallberg A. Rosenström U, et al. Among authors: botros m. J Med Chem. 2006 Oct 5;49(20):6133-7. doi: 10.1021/jm051222g. J Med Chem. 2006. PMID: 17004728

8

Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships.

Wu X, Wan Y, Mahalingam AK, Murugaiah AM, Plouffe B, Botros M, Karlén A, Hallberg M, Gallo-Payet N, Alterman M. Wu X, et al. Among authors: botros m. J Med Chem. 2006 Nov 30;49(24):7160-8. doi: 10.1021/jm0606185. J Med Chem. 2006. PMID: 17125268

9

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.

Georgsson J, Sköld C, Botros M, Lindeberg G, Nyberg F, Karlén A, Hallberg A, Larhed M. Georgsson J, et al. Among authors: botros m. J Med Chem. 2007 Apr 5;50(7):1711-5. doi: 10.1021/jm0613469. Epub 2007 Mar 15. J Med Chem. 2007. PMID: 17358051

10

Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.

Murugaiah AM, Wallinder C, Mahalingam AK, Wu X, Wan Y, Plouffe B, Botros M, Karlén A, Hallberg M, Gallo-Payet N, Alterman M. Murugaiah AM, et al. Among authors: botros m. Bioorg Med Chem. 2007 Nov 15;15(22):7166-83. doi: 10.1016/j.bmc.2007.07.026. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17825570

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