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VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression.
Woolard J, Wang WY, Bevan HS, Qiu Y, Morbidelli L, Pritchard-Jones RO, Cui TG, Sugiono M, Waine E, Perrin R, Foster R, Digby-Bell J, Shields JD, Whittles CE, Mushens RE, Gillatt DA, Ziche M, Harper SJ, Bates DO. Woolard J, et al. Among authors: shields jd. Cancer Res. 2004 Nov 1;64(21):7822-35. doi: 10.1158/0008-5472.CAN-04-0934. Cancer Res. 2004. PMID: 15520188
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
Mlynarski SN, Aquila BM, Cantin S, Cook S, Doshi A, Finlay MRV, Gangl ET, Grebe T, Gu C, Kawatkar SP, Petersen J, Pop-Damkov P, Schuller AG, Shao W, Shields JD, Simpson I, Tavakoli S, Tentarelli S, Throner S, Wang H, Wang J, Wu D, Ye Q. Mlynarski SN, et al. Among authors: shields jd. J Med Chem. 2024 Dec 12;67(23):20827-20841. doi: 10.1021/acs.jmedchem.4c02309. Epub 2024 Nov 21. J Med Chem. 2024. PMID: 39572889
106 results