Christman JK - Search Results

1

Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain.

Marquez VE, Eritja R, Kelley JA, Vanbemmel D, Christman JK. Marquez VE, et al. Among authors: christman jk. Ann N Y Acad Sci. 2003 Dec;1002:154-64. doi: 10.1196/annals.1281.014. Ann N Y Acad Sci. 2003. PMID: 14751833

2

DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.

van Bemmel DM, Brank AS, Eritja R, Marquez VE, Christman JK. van Bemmel DM, et al. Among authors: christman jk. Biochem Pharmacol. 2009 Sep 15;78(6):633-41. doi: 10.1016/j.bcp.2009.05.017. Epub 2009 May 23. Biochem Pharmacol. 2009. PMID: 19467223 Free PMC article.

3

Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation.

Brank AS, Eritja R, Garcia RG, Marquez VE, Christman JK. Brank AS, et al. Among authors: christman jk. J Mol Biol. 2002 Oct 11;323(1):53-67. doi: 10.1016/s0022-2836(02)00918-x. J Mol Biol. 2002. PMID: 12368098 Free article.

4

Inhibition of (cytosine C5)-methyltransferase by oligonucleotides containing flexible (cyclopentane) and conformationally constrained (bicyclo[3.1.0]hexane) abasic sites.

Marquez VE, Wang P, Nicklaus MC, Maier M, Manoharan M, Christman JK, Banavali NK, Mackerell AD Jr. Marquez VE, et al. Among authors: christman jk. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):451-9. doi: 10.1081/NCN-100002319. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563060 Review.

5

Synthesis of oligonucleotide inhibitors of DNA (Cytosine-C5) methyltransferase containing 5-azacytosine residues at specific sites.

Güimil García R, Brank AS, Christman JK, Marquez VE, Eritja R. Güimil García R, et al. Among authors: christman jk. Antisense Nucleic Acid Drug Dev. 2001 Dec;11(6):369-78. doi: 10.1089/108729001753411335. Antisense Nucleic Acid Drug Dev. 2001. PMID: 11838638

6

Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.

Sheikhnejad G, Brank A, Christman JK, Goddard A, Alvarez E, Ford H Jr, Marquez VE, Marasco CJ, Sufrin JR, O'gara M, Cheng X. Sheikhnejad G, et al. Among authors: christman jk. J Mol Biol. 1999 Feb 5;285(5):2021-34. doi: 10.1006/jmbi.1998.2426. J Mol Biol. 1999. PMID: 9925782

7

Optimization of baculovirus-mediated expression and purification of hexahistidine-tagged murine DNA (cytosine-C5)-methyltransferase-1 in Spodoptera frugiperda 9 cells.

Brank AS, Van Bemmel DM, Christman JK. Brank AS, et al. Among authors: christman jk. Protein Expr Purif. 2002 Jun;25(1):31-40. doi: 10.1006/prep.2001.1606. Protein Expr Purif. 2002. PMID: 12071696

8

p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas.

Lee MS, Igawa T, Chen SJ, Van Bemmel D, Lin JS, Lin FF, Johansson SL, Christman JK, Lin MF. Lee MS, et al. Among authors: christman jk. Int J Cancer. 2004 Feb 20;108(5):672-8. doi: 10.1002/ijc.11621. Int J Cancer. 2004. PMID: 14696093

9

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation.

Christman JK, Sheikhnejad G, Marasco CJ, Sufrin JR. Christman JK, et al. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7347-51. doi: 10.1073/pnas.92.16.7347. Proc Natl Acad Sci U S A. 1995. PMID: 7638194 Free PMC article.

10

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

Christman JK. Christman JK. Oncogene. 2002 Aug 12;21(35):5483-95. doi: 10.1038/sj.onc.1205699. Oncogene. 2002. PMID: 12154409 Review.

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