de Vries A - Search Results

1

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer.

Attardi LD, de Vries A, Jacks T. Attardi LD, et al. Among authors: de vries a. Oncogene. 2004 Jan 29;23(4):973-80. doi: 10.1038/sj.onc.1207026. Oncogene. 2004. PMID: 14749764

2

Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.

Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G. Iwakuma T, et al. Among authors: de vries a. Oncogene. 2004 Oct 7;23(46):7644-50. doi: 10.1038/sj.onc.1207793. Oncogene. 2004. PMID: 15361844

3

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

Bruins W, Zwart E, Attardi LD, Iwakuma T, Hoogervorst EM, Beems RB, Miranda B, van Oostrom CT, van den Berg J, van den Aardweg GJ, Lozano G, van Steeg H, Jacks T, de Vries A. Bruins W, et al. Among authors: de vries a. Mol Cell Biol. 2004 Oct;24(20):8884-94. doi: 10.1128/MCB.24.20.8884-8894.2004. Mol Cell Biol. 2004. PMID: 15456863 Free PMC article.

4

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.

Wijnhoven SW, Speksnijder EN, Liu X, Zwart E, vanOostrom CT, Beems RB, Hoogervorst EM, Schaap MM, Attardi LD, Jacks T, van Steeg H, Jonkers J, de Vries A. Wijnhoven SW, et al. Among authors: de vries a. Cancer Res. 2007 May 15;67(10):4648-56. doi: 10.1158/0008-5472.CAN-06-4681. Cancer Res. 2007. PMID: 17510390

5

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

MacPherson D, Kim J, Kim T, Rhee BK, Van Oostrom CT, DiTullio RA, Venere M, Halazonetis TD, Bronson R, De Vries A, Fleming M, Jacks T. MacPherson D, et al. Among authors: de vries a. EMBO J. 2004 Sep 15;23(18):3689-99. doi: 10.1038/sj.emboj.7600363. Epub 2004 Sep 2. EMBO J. 2004. PMID: 15343266 Free PMC article.

6

Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.

Hoogervorst EM, Bruins W, Zwart E, van Oostrom CT, van den Aardweg GJ, Beems RB, van den Berg J, Jacks T, van Steeg H, de Vries A. Hoogervorst EM, et al. Among authors: de vries a. Cancer Res. 2005 May 1;65(9):3610-6. doi: 10.1158/0008-5472.CAN-04-4328. Cancer Res. 2005. PMID: 15867355

7

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function.

de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. de Vries A, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2948-53. doi: 10.1073/pnas.052713099. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867759 Free PMC article.

8

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Wijnhoven SW, Zwart E, Speksnijder EN, Beems RB, Olive KP, Tuveson DA, Jonkers J, Schaap MM, van den Berg J, Jacks T, van Steeg H, de Vries A. Wijnhoven SW, et al. Among authors: de vries a. Cancer Res. 2005 Sep 15;65(18):8166-73. doi: 10.1158/0008-5472.CAN-05-1650. Cancer Res. 2005. PMID: 16166291

9

The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts.

Bruins W, Bruning O, Jonker MJ, Zwart E, van der Hoeven TV, Pennings JL, Rauwerda H, de Vries A, Breit TM. Bruins W, et al. Among authors: de vries a. Mol Cell Biol. 2008 Mar;28(6):1974-87. doi: 10.1128/MCB.01610-07. Epub 2008 Jan 14. Mol Cell Biol. 2008. PMID: 18195040 Free PMC article.

10

XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.

de Vries A, Berg RJ, Wijnhoven S, Westerman A, Wester PW, van Kreijl CF, Capel PJ, de Gruijl FR, van Kranen HJ, van Steeg H. de Vries A, et al. Among authors: de gruijl fr. Oncogene. 1998 Apr 30;16(17):2205-12. doi: 10.1038/sj.onc.1201744. Oncogene. 1998. PMID: 9619829

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