Brands M - Search Results

1

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.

Beyer D, Kroll HP, Endermann R, Schiffer G, Siegel S, Bauser M, Pohlmann J, Brands M, Ziegelbauer K, Haebich D, Eymann C, Brötz-Oesterhelt H. Beyer D, et al. Among authors: brands m. Antimicrob Agents Chemother. 2004 Feb;48(2):525-32. doi: 10.1128/AAC.48.2.525-532.2004. Antimicrob Agents Chemother. 2004. PMID: 14742205 Free PMC article.

2

Identification and characterization of the first class of potent bacterial acetyl-CoA carboxylase inhibitors with antibacterial activity.

Freiberg C, Brunner NA, Schiffer G, Lampe T, Pohlmann J, Brands M, Raabe M, Häbich D, Ziegelbauer K. Freiberg C, et al. Among authors: brands m. J Biol Chem. 2004 Jun 18;279(25):26066-73. doi: 10.1074/jbc.M402989200. Epub 2004 Apr 2. J Biol Chem. 2004. PMID: 15066985 Free article.

3

Biological characterization of novel inhibitors of the gram-positive DNA polymerase IIIC enzyme.

Kuhl A, Svenstrup N, Ladel C, Otteneder M, Binas A, Schiffer G, Brands M, Lampe T, Ziegelbauer K, Rübsamen-Waigmann H, Haebich D, Ehlert K. Kuhl A, et al. Among authors: brands m. Antimicrob Agents Chemother. 2005 Mar;49(3):987-95. doi: 10.1128/AAC.49.3.987-995.2005. Antimicrob Agents Chemother. 2005. PMID: 15728893 Free PMC article.

4

Dihydropyrimidinones--a new class of anti-staphylococcal antibiotics.

Brands M, Endermann R, Gahlmann R, Krüger J, Raddatz S. Brands M, et al. Bioorg Med Chem Lett. 2003 Jan 20;13(2):241-5. doi: 10.1016/s0960-894x(02)00880-6. Bioorg Med Chem Lett. 2003. PMID: 12482431

5

Novel antibiotics for the treatment of gram-positive bacterial infections.

Brands M, Endermann R, Gahlmann R, Krüger J, Raddatz S, Stoltefuss J, Belov VN, Nizamov S, Sokolov VV, de Meijere A. Brands M, et al. J Med Chem. 2002 Sep 12;45(19):4246-53. doi: 10.1021/jm0111191. J Med Chem. 2002. PMID: 12213065

6

Pyrimidinone antibiotics--heterocyclic analogues with improved antibacterial spectrum.

Brands M, Grande YC, Endermann R, Gahlmann R, Krüger J, Raddatz S. Brands M, et al. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2641-5. doi: 10.1016/s0960-894x(03)00578-x. Bioorg Med Chem Lett. 2003. PMID: 12873484

7

Novel, selective indole-based ECE inhibitors: lead optimization via solid-phase and classical synthesis.

Brands M, Ergüden JK, Hashimoto K, Heimbach D, Schröder C, Siegel S, Stasch JP, Weigand S. Brands M, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4201-5. doi: 10.1016/j.bmcl.2005.06.085. Bioorg Med Chem Lett. 2005. PMID: 16085415

8

Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.

Brands M, Ergüden JK, Hashimoto K, Heimbach D, Krahn T, Schröder C, Siegel S, Stasch JP, Tsujishita H, Weigand S, Yoshida NH. Brands M, et al. ChemMedChem. 2006 Jan;1(1):96-105. doi: 10.1002/cmdc.200500009. ChemMedChem. 2006. PMID: 16892341

9

Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity.

Wengner AM, Siemeister G, Koppitz M, Schulze V, Kosemund D, Klar U, Stoeckigt D, Neuhaus R, Lienau P, Bader B, Prechtl S, Raschke M, Frisk AL, von Ahsen O, Michels M, Kreft B, von Nussbaum F, Brands M, Mumberg D, Ziegelbauer K. Wengner AM, et al. Among authors: brands m. Mol Cancer Ther. 2016 Apr;15(4):583-92. doi: 10.1158/1535-7163.MCT-15-0500. Epub 2016 Feb 1. Mol Cancer Ther. 2016. PMID: 26832791

10

Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo.

Siemeister G, Mengel A, Fernández-Montalván AE, Bone W, Schröder J, Zitzmann-Kolbe S, Briem H, Prechtl S, Holton SJ, Mönning U, von Ahsen O, Johanssen S, Cleve A, Pütter V, Hitchcock M, von Nussbaum F, Brands M, Ziegelbauer K, Mumberg D. Siemeister G, et al. Among authors: brands m. Clin Cancer Res. 2019 Feb 15;25(4):1404-1414. doi: 10.1158/1078-0432.CCR-18-0628. Epub 2018 Nov 14. Clin Cancer Res. 2019. PMID: 30429199

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