Tourwé D - Search Results

1

Structure-activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues.

Tömböly C, Kövér KE, Péter A, Tourwé D, Biyashev D, Benyhe S, Borsodi A, Al-Khrasani M, Rónai AZ, Tóth G. Tömböly C, et al. Among authors: tourwe d. J Med Chem. 2004 Jan 29;47(3):735-43. doi: 10.1021/jm0310028. J Med Chem. 2004. PMID: 14736254

2

Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.

Tóth G, Ioja E, Tömböly C, Ballet S, Tourwé D, Péter A, Martinek T, Chung NN, Schiller PW, Benyhe S, Borsodi A. Tóth G, et al. Among authors: tourwe d. J Med Chem. 2007 Jan 25;50(2):328-33. doi: 10.1021/jm060721u. J Med Chem. 2007. PMID: 17228874

3

Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.

Ioja E, Tourwé D, Kertész I, Tóth G, Borsodi A, Benyhe S. Ioja E, et al. Among authors: tourwe d. Brain Res Bull. 2007 Sep 14;74(1-3):119-29. doi: 10.1016/j.brainresbull.2007.05.010. Epub 2007 Jun 8. Brain Res Bull. 2007. PMID: 17683797

4

Endomorphin-2 with a beta-turn backbone constraint retains the potent micro-opioid receptor agonist properties.

Tömböly C, Ballet S, Feytens D, Kövér KE, Borics A, Lovas S, Al-Khrasani M, Fürst Z, Tóth G, Benyhe S, Tourwé D. Tömböly C, et al. Among authors: tourwe d. J Med Chem. 2008 Jan 10;51(1):173-7. doi: 10.1021/jm7010222. Epub 2007 Dec 7. J Med Chem. 2008. PMID: 18062664

5

Design, synthesis, pharmacological evaluation, and structure-activity study of novel endomorphin analogues with multiple structural modifications.

Mallareddy JR, Borics A, Keresztes A, Kövér KE, Tourwé D, Tóth G. Mallareddy JR, et al. Among authors: tourwe d. J Med Chem. 2011 Mar 10;54(5):1462-72. doi: 10.1021/jm101515v. Epub 2011 Feb 2. J Med Chem. 2011. PMID: 21287991

6

Opioid receptor binding characteristics and structure-activity studies of novel tetrapeptides in the TIPP (Tyr-Tic-Phe-Phe) series.

Ioja E, Tóth G, Benyhe S, Tourwe D, Péter A, Tömböly C, Borsodi A. Ioja E, et al. Among authors: tourwe d. Neurosignals. 2005;14(6):317-28. doi: 10.1159/000093046. Neurosignals. 2005. PMID: 16772734

7

Conformationally constrained deltorphin analogs with 2-aminotetralin-2-carboxylic acid in position 3.

Tóth G, Darula Z, Péter A, Fülöp F, Tourwé D, Jaspers H, Verheyden P, Böcskey Z, Tóth Z, Borsodi A. Tóth G, et al. Among authors: tourwe d. J Med Chem. 1997 Mar 14;40(6):990-5. doi: 10.1021/jm9602726. J Med Chem. 1997. PMID: 9083489

8

Deltorphin II analogues with 6-hydroxy-2-aminotetralin-2-carboxylic acid in position 1.

Darula Z, Kövér KE, Monory K, Borsodi A, Makó E, Rónai A, Tourwé D, Péter A, Tóth G. Darula Z, et al. Among authors: tourwe d. J Med Chem. 2000 Apr 6;43(7):1359-66. doi: 10.1021/jm9911534. J Med Chem. 2000. PMID: 10753473

9

Synthesis, biological evaluation, and automated docking of constrained analogues of the opioid peptide H-Dmt-D-Ala-Phe-Gly-NH₂ using the 4- or 5-methyl substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one scaffold.

De Wachter R, de Graaf C, Keresztes A, Vandormael B, Ballet S, Tóth G, Rognan D, Tourwé D. De Wachter R, et al. Among authors: tourwe d. J Med Chem. 2011 Oct 13;54(19):6538-47. doi: 10.1021/jm2003574. Epub 2011 Sep 14. J Med Chem. 2011. PMID: 21870874

10

Development of potent and proteolytically stable human neuromedin U receptor agonists.

De Prins A, Martin C, Van Wanseele Y, Skov LJ, Tömböly C, Tourwé D, Caveliers V, Van Eeckhaut A, Holst B, Rosenkilde MM, Smolders I, Ballet S. De Prins A, et al. Among authors: tourwe d. Eur J Med Chem. 2018 Jan 20;144:887-897. doi: 10.1016/j.ejmech.2017.12.035. Epub 2017 Dec 14. Eur J Med Chem. 2018. PMID: 29329072 Free article.

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