Ramos JA - Search Results

1

Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: synthesis of new transporter inhibitors as tools for this study.

Ruiz-Llorente L, Ortega-Gutiérrez S, Viso A, Sánchez MG, Sánchez AM, Fernández C, Ramos JA, Hillard C, Lasunción MA, López-Rodríguez ML, Díaz-Laviada I. Ruiz-Llorente L, et al. Among authors: ramos ja. Br J Pharmacol. 2004 Feb;141(3):457-67. doi: 10.1038/sj.bjp.0705628. Epub 2004 Jan 12. Br J Pharmacol. 2004. PMID: 14718261 Free PMC article.

2

UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide.

de Lago E, Fernández-Ruiz J, Ortega-Gutiérrez S, Viso A, López-Rodríguez ML, Ramos JA. de Lago E, et al. Among authors: ramos ja. Eur J Pharmacol. 2002 Aug 2;449(1-2):99-103. doi: 10.1016/s0014-2999(02)01996-9. Eur J Pharmacol. 2002. PMID: 12163112

3

Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase.

López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Fowler CJ, Tiger G, de Lago E, Fernández-Ruiz J, Ramos JA. López-Rodríguez ML, et al. Among authors: ramos ja. J Med Chem. 2003 Apr 10;46(8):1512-22. doi: 10.1021/jm0210818. J Med Chem. 2003. PMID: 12672252

4

Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors.

López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Fowler CJ, Tiger G, de Lago E, Fernández-Ruiz J, Ramos JA. López-Rodríguez ML, et al. Among authors: ramos ja. Eur J Med Chem. 2003 Apr;38(4):403-12. doi: 10.1016/s0223-5234(03)00045-x. Eur J Med Chem. 2003. PMID: 12750028

5

UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.

de Lago E, Fernández-Ruiz J, Ortega-Gutiérrez S, Cabranes A, Pryce G, Baker D, López-Rodríguez M, Ramos JA. de Lago E, et al. Among authors: ramos ja. Eur Neuropsychopharmacol. 2006 Jan;16(1):7-18. doi: 10.1016/j.euroneuro.2005.06.001. Epub 2005 Jul 11. Eur Neuropsychopharmacol. 2006. PMID: 16006105

6

Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin.

Fowler CJ, Tiger G, López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Ramos JA. Fowler CJ, et al. Among authors: ramos ja. J Enzyme Inhib Med Chem. 2003 Jun;18(3):225-31. doi: 10.1080/1475636031000080216. J Enzyme Inhib Med Chem. 2003. PMID: 14506913 Free article.

7

Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions.

de Lago E, Ortega-Gutiérrez S, Ramos JA, López Rodríguez ML, Fernández-Ruiz J. de Lago E, et al. Among authors: ramos ja. Life Sci. 2007 Feb 13;80(10):979-88. doi: 10.1016/j.lfs.2006.11.029. Epub 2006 Nov 23. Life Sci. 2007. PMID: 17173937

8

Synthesis and structure-activity relationships of a new model of arylpiperazines. Part 7: Study of the influence of lipophilic factors at the terminal amide fragment on 5-HT(1A) affinity/selectivity.

López-Rodríguez ML, Ayala D, Viso A, Benhamú B, de La Pradilla RF, Zarza F, Ramos JA. López-Rodríguez ML, et al. Among authors: ramos ja. Bioorg Med Chem. 2004 Mar 15;12(6):1551-7. doi: 10.1016/j.bmc.2003.12.006. Bioorg Med Chem. 2004. PMID: 15018929

9

Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.

López-Rodríguez ML, Porras E, Morcillo MJ, Benhamú B, Soto LJ, Lavandera JL, Ramos JA, Olivella M, Campillo M, Pardo L. López-Rodríguez ML, et al. Among authors: ramos ja. J Med Chem. 2003 Dec 18;46(26):5638-50. doi: 10.1021/jm030841r. J Med Chem. 2003. PMID: 14667218

10

New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.

Valhondo M, Marco I, Martín-Fontecha M, Vázquez-Villa H, Ramos JA, Berkels R, Lauterbach T, Benhamú B, López-Rodríguez ML. Valhondo M, et al. Among authors: ramos ja. J Med Chem. 2013 Oct 24;56(20):7851-61. doi: 10.1021/jm400766k. Epub 2013 Oct 8. J Med Chem. 2013. PMID: 24050112

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