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Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors.
Lehtonen R, Kiuru M, Vanharanta S, Sjöberg J, Aaltonen LM, Aittomäki K, Arola J, Butzow R, Eng C, Husgafvel-Pursiainen K, Isola J, Järvinen H, Koivisto P, Mecklin JP, Peltomäki P, Salovaara R, Wasenius VM, Karhu A, Launonen V, Nupponen NN, Aaltonen LA. Lehtonen R, et al. Among authors: jarvinen h. Am J Pathol. 2004 Jan;164(1):17-22. doi: 10.1016/S0002-9440(10)63091-X. Am J Pathol. 2004. PMID: 14695314 Free PMC article.
Little evidence for involvement of MLH3 in colorectal cancer predisposition.
Hienonen T, Laiho P, Salovaara R, Mecklin JP, Järvinen H, Sistonen P, Peltomäki P, Lehtonen R, Nupponen NN, Launonen V, Karhu A, Aaltonen LA. Hienonen T, et al. Among authors: jarvinen h. Int J Cancer. 2003 Aug 20;106(2):292-6. doi: 10.1002/ijc.11218. Int J Cancer. 2003. PMID: 12800209
LKB1 somatic mutations in sporadic tumors.
Avizienyte E, Loukola A, Roth S, Hemminki A, Tarkkanen M, Salovaara R, Arola J, Bützow R, Husgafvel-Pursiainen K, Kokkola A, Järvinen H, Aaltonen LA. Avizienyte E, et al. Among authors: jarvinen h. Am J Pathol. 1999 Mar;154(3):677-81. doi: 10.1016/S0002-9440(10)65314-X. Am J Pathol. 1999. PMID: 10079245 Free PMC article.
Microsatellite instability in adenomas as a marker for hereditary nonpolyposis colorectal cancer.
Loukola A, Salovaara R, Kristo P, Moisio AL, Kääriäinen H, Ahtola H, Eskelinen M, Härkönen N, Julkunen R, Kangas E, Ojala S, Tulikoura J, Valkamo E, Järvinen H, Mecklin JP, de la Chapelle A, Aaltonen LA. Loukola A, et al. Among authors: jarvinen h. Am J Pathol. 1999 Dec;155(6):1849-53. doi: 10.1016/S0002-9440(10)65503-4. Am J Pathol. 1999. PMID: 10595914 Free PMC article.
430 results