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Page 1
Peptide ketobenzoxazole inhibitors bound to cathepsin K.
McGrath ME, Sprengeler PA, Hill CM, Martichonok V, Cheung H, Somoza JR, Palmer JT, Janc JW. McGrath ME, et al. Among authors: somoza jr. Biochemistry. 2003 Dec 30;42(51):15018-28. doi: 10.1021/bi035041x. Biochemistry. 2003. PMID: 14690410
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.
Palmer JT, Bryant C, Wang DX, Davis DE, Setti EL, Rydzewski RM, Venkatraman S, Tian ZQ, Burrill LC, Mendonca RV, Springman E, McCarter J, Chung T, Cheung H, Janc JW, McGrath M, Somoza JR, Enriquez P, Yu ZW, Strickley RM, Liu L, Venuti MC, Percival MD, Falgueyret JP, Prasit P, Oballa R, Riendeau D, Young RN, Wesolowski G, Rodan SB, Johnson C, Kimmel DB, Rodan G. Palmer JT, et al. Among authors: somoza jr. J Med Chem. 2005 Dec 1;48(24):7520-34. doi: 10.1021/jm058198r. J Med Chem. 2005. PMID: 16302794
Structure-guided design of peptide-based tryptase inhibitors.
McGrath ME, Sprengeler PA, Hirschbein B, Somoza JR, Lehoux I, Janc JW, Gjerstad E, Graupe M, Estiarte A, Venkataramani C, Liu Y, Yee R, Ho JD, Green MJ, Lee CS, Liu L, Tai V, Spencer J, Sperandio D, Katz BA. McGrath ME, et al. Among authors: somoza jr. Biochemistry. 2006 May 16;45(19):5964-73. doi: 10.1021/bi060173m. Biochemistry. 2006. PMID: 16681368
Crystal structure of human cathepsin V.
Somoza JR, Zhan H, Bowman KK, Yu L, Mortara KD, Palmer JT, Clark JM, McGrath ME. Somoza JR, et al. Biochemistry. 2000 Oct 17;39(41):12543-51. doi: 10.1021/bi000951p. Biochemistry. 2000. PMID: 11027133
Crystal structure of human cathepsin S.
McGrath ME, Palmer JT, Brömme D, Somoza JR. McGrath ME, et al. Among authors: somoza jr. Protein Sci. 1998 Jun;7(6):1294-302. doi: 10.1002/pro.5560070604. Protein Sci. 1998. PMID: 9655332 Free PMC article.
38 results