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Gastrointestinal stromal tumors with internal tandem duplications in 3' end of KIT juxtamembrane domain occur predominantly in stomach and generally seem to have a favorable course.
Lasota J, Dansonka-Mieszkowska A, Stachura T, Schneider-Stock R, Kallajoki M, Steigen SE, Sarlomo-Rikala M, Boltze C, Kordek R, Roessner A, Stachura J, Miettinen M. Lasota J, et al. Mod Pathol. 2003 Dec;16(12):1257-64. doi: 10.1097/01.MP.0000097365.72526.3E. Mod Pathol. 2003. PMID: 14681327
Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors.
Lasota J, vel Dobosz AJ, Wasag B, Wozniak A, Kraszewska E, Michej W, Ptaszynski K, Rutkowski P, Sarlomo-Rikala M, Steigen SE, Schneider-Stock R, Stachura J, Chosia M, Ogun G, Ruka W, Siedlecki JA, Miettinen M. Lasota J, et al. Lab Invest. 2007 Oct;87(10):1029-41. doi: 10.1038/labinvest.3700628. Epub 2007 Jul 16. Lab Invest. 2007. PMID: 17632543 Free article.
247 results