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CD40L modulates CD4+ T-cell activation through receptor for activated C kinase 1.
van Os BW, Vos WG, Bosmans LA, van Tiel CM, Toom MD, Beckers L, Admiraal M, Hoeksema MA, de Winther MP, Lutgens E. van Os BW, et al. Among authors: beckers l. Eur J Immunol. 2023 Dec;53(12):e2350520. doi: 10.1002/eji.202350520. Epub 2023 Nov 20. Eur J Immunol. 2023. PMID: 37683186 Free article.
Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis.
van Os BW, Kusters PJH, den Toom M, Beckers L, van Tiel CM, Vos WG, de Jong E, Kieser A, van Roomen C, Binder CJ, Reiche ME, de Winther MP, Bosmans LA, Lutgens E. van Os BW, et al. Among authors: beckers l. Front Cardiovasc Med. 2023 May 5;10:1171764. doi: 10.3389/fcvm.2023.1171764. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37215541 Free PMC article.
Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes.
Stöger JL, Boshuizen MC, Brufau G, Gijbels MJ, Wolfs IM, van der Velden S, Pöttgens CC, Vergouwe MN, Wijnands E, Beckers L, Goossens P, Kerksiek A, Havinga R, Müller W, Lütjohann D, Groen AK, de Winther MP. Stöger JL, et al. Among authors: beckers l. Thromb Haemost. 2016 Aug 30;116(3):565-77. doi: 10.1160/TH16-01-0043. Epub 2016 Jun 30. Thromb Haemost. 2016. PMID: 27358035
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.
Aarts SABM, Seijkens TTP, Kusters PJH, van der Pol SMA, Zarzycka B, Heijnen PDAM, Beckers L, den Toom M, Gijbels MJJ, Boon L, Weber C, de Vries HE, Nicolaes GAF, Dijkstra CD, Kooij G, Lutgens E. Aarts SABM, et al. Among authors: beckers l. J Neuroinflammation. 2017 May 12;14(1):105. doi: 10.1186/s12974-017-0875-9. J Neuroinflammation. 2017. PMID: 28494768 Free PMC article.
Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction.
Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E. Aarts SABM, et al. Among authors: beckers l. PLoS One. 2018 Aug 10;13(8):e0202150. doi: 10.1371/journal.pone.0202150. eCollection 2018. PLoS One. 2018. PMID: 30096208 Free PMC article.
Adipocytes control hematopoiesis and inflammation through CD40 signaling.
Reiche ME, Poels K, Bosmans LA, Vos WG, Van Tiel CM, Gijbels MJJ, Aarts SABM, Den Toom M, Beckers L, Weber C, Atzler D, Rensen PCN, Kooijman S, Lutgens E. Reiche ME, et al. Among authors: beckers l. Haematologica. 2023 Jul 1;108(7):1873-1885. doi: 10.3324/haematol.2022.281482. Haematologica. 2023. PMID: 36475519 Free PMC article.
158 results