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Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface.
Wooldridge L, Hutchinson SL, Choi EM, Lissina A, Jones E, Mirza F, Dunbar PR, Price DA, Cerundolo V, Sewell AK. Wooldridge L, et al. Among authors: lissina a. J Immunol. 2003 Dec 15;171(12):6650-60. doi: 10.4049/jimmunol.171.12.6650. J Immunol. 2003. PMID: 14662868
High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Choi EM, Chen JL, Wooldridge L, Salio M, Lissina A, Lissin N, Hermans IF, Silk JD, Mirza F, Palmowski MJ, Dunbar PR, Jakobsen BK, Sewell AK, Cerundolo V. Choi EM, et al. Among authors: lissina a. J Immunol. 2003 Nov 15;171(10):5116-23. doi: 10.4049/jimmunol.171.10.5116. J Immunol. 2003. PMID: 14607910
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Wooldridge L, Clement M, Lissina A, Edwards ES, Ladell K, Ekeruche J, Hewitt RE, Laugel B, Gostick E, Cole DK, Debets R, Berrevoets C, Miles JJ, Burrows SR, Price DA, Sewell AK. Wooldridge L, et al. Among authors: lissina a. J Immunol. 2010 Apr 1;184(7):3357-66. doi: 10.4049/jimmunol.0902398. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190139 Free PMC article.
Tricks with tetramers: how to get the most from multimeric peptide-MHC.
Wooldridge L, Lissina A, Cole DK, van den Berg HA, Price DA, Sewell AK. Wooldridge L, et al. Among authors: lissina a. Immunology. 2009 Feb;126(2):147-64. doi: 10.1111/j.1365-2567.2008.02848.x. Immunology. 2009. PMID: 19125886 Free PMC article. Review.
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.
Ekeruche-Makinde J, Clement M, Cole DK, Edwards ES, Ladell K, Miles JJ, Matthews KK, Fuller A, Lloyd KA, Madura F, Dolton GM, Pentier J, Lissina A, Gostick E, Baxter TK, Baker BM, Rizkallah PJ, Price DA, Wooldridge L, Sewell AK. Ekeruche-Makinde J, et al. Among authors: lissina a. J Biol Chem. 2012 Oct 26;287(44):37269-81. doi: 10.1074/jbc.M112.386409. Epub 2012 Sep 5. J Biol Chem. 2012. PMID: 22952231 Free PMC article.
Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers.
Melenhorst JJ, Scheinberg P, Chattopadhyay PK, Lissina A, Gostick E, Cole DK, Wooldridge L, van den Berg HA, Bornstein E, Hensel NF, Douek DC, Roederer M, Sewell AK, Barrett AJ, Price DA. Melenhorst JJ, et al. Among authors: lissina a. J Immunol Methods. 2008 Sep 30;338(1-2):31-9. doi: 10.1016/j.jim.2008.07.008. Epub 2008 Jul 31. J Immunol Methods. 2008. PMID: 18675271 Free PMC article.
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.
Lissina A, Ladell K, Skowera A, Clement M, Edwards E, Seggewiss R, van den Berg HA, Gostick E, Gallagher K, Jones E, Melenhorst JJ, Godkin AJ, Peakman M, Price DA, Sewell AK, Wooldridge L. Lissina A, et al. J Immunol Methods. 2009 Jan 1;340(1):11-24. doi: 10.1016/j.jim.2008.09.014. Epub 2008 Oct 16. J Immunol Methods. 2009. PMID: 18929568 Free PMC article.
29 results