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Validation study of a method for assaying DE-310, a macromolecular carrier conjugate containing an anti-tumor camptothecin derivative, and the free drug in human plasma by HPLC and LC/MS/MS.
Oguma T, Cicci D, Gaudette F, Gauthier-Dubois G, Guilbaud R, Atsumi R. Oguma T, et al. Among authors: atsumi r. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Apr 25;818(2):249-56. doi: 10.1016/j.jchromb.2005.01.005. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15734166
Validation study of a method for assaying DE-310, a macromolecular carrier conjugate containing an anti-tumor camptothecin derivative, and the free drug in tumor tissue by high performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry.
Oguma T, Morikawa H, Iwasaki D, Atsumi R. Oguma T, et al. Among authors: atsumi r. Biomed Chromatogr. 2005 Jan;19(1):19-26. doi: 10.1002/bmc.409. Biomed Chromatogr. 2005. PMID: 15484225
Phase I and pharmacokinetic study of TZT-1027, a novel synthetic dolastatin 10 derivative, administered as a 1-hour intravenous infusion every 3 weeks in patients with advanced refractory cancer.
Schöffski P, Thate B, Beutel G, Bolte O, Otto D, Hofmann M, Ganser A, Jenner A, Cheverton P, Wanders J, Oguma T, Atsumi R, Satomi M. Schöffski P, et al. Among authors: atsumi r. Ann Oncol. 2004 Apr;15(4):671-9. doi: 10.1093/annonc/mdh141. Ann Oncol. 2004. PMID: 15033678 Free article. Clinical Trial.
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