Waksman G - Search Results

1

The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances.

Kumaran S, Grucza RA, Waksman G. Kumaran S, et al. Among authors: waksman g. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14828-33. doi: 10.1073/pnas.2432867100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657388 Free PMC article.

2

SH2 domains: role, structure and implications for molecular medicine.

Waksman G, Kumaran S, Lubman O. Waksman G, et al. Expert Rev Mol Med. 2004 Jan 30;6(3):1-18. doi: 10.1017/S1462399404007331. Expert Rev Mol Med. 2004. PMID: 14987415 Review.

3

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.

Fütterer K, Wong J, Grucza RA, Chan AC, Waksman G. Fütterer K, et al. Among authors: waksman g. J Mol Biol. 1998 Aug 21;281(3):523-37. doi: 10.1006/jmbi.1998.1964. J Mol Biol. 1998. PMID: 9698567

4

Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers.

Grucza RA, Fütterer K, Chan AC, Waksman G. Grucza RA, et al. Among authors: waksman g. Biochemistry. 1999 Apr 20;38(16):5024-33. doi: 10.1021/bi9829938. Biochemistry. 1999. PMID: 10213605

5

Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase.

Grucza RA, Bradshaw JM, Mitaxov V, Waksman G. Grucza RA, et al. Among authors: waksman g. Biochemistry. 2000 Aug 22;39(33):10072-81. doi: 10.1021/bi000891n. Biochemistry. 2000. PMID: 10955995

6

pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein.

Réty S, Fütterer K, Grucza RA, Munoz CM, Frazier WA, Waksman G. Réty S, et al. Among authors: waksman g. Protein Sci. 1996 Mar;5(3):405-13. doi: 10.1002/pro.5560050301. Protein Sci. 1996. PMID: 8868476 Free PMC article.

7

Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study.

Bradshaw JM, Grucza RA, Ladbury JE, Waksman G. Bradshaw JM, et al. Among authors: waksman g. Biochemistry. 1998 Jun 23;37(25):9083-90. doi: 10.1021/bi973147k. Biochemistry. 1998. PMID: 9636054

8

SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships.

Grucza RA, Bradshaw JM, Fütterer K, Waksman G. Grucza RA, et al. Among authors: waksman g. Med Res Rev. 1999 Jul;19(4):273-93. doi: 10.1002/(sici)1098-1128(199907)19:4<273::aid-med2>3.0.co;2-g. Med Res Rev. 1999. PMID: 10398925 Review. No abstract available.

9

Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.

Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G. Korolev S, et al. Among authors: waksman g. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9264-8. doi: 10.1073/pnas.92.20.9264. Proc Natl Acad Sci U S A. 1995. PMID: 7568114 Free PMC article.

10

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity.

Cheng W, Brendza KM, Gauss GH, Korolev S, Waksman G, Lohman TM. Cheng W, et al. Among authors: waksman g. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16006-11. doi: 10.1073/pnas.242479399. Epub 2002 Nov 19. Proc Natl Acad Sci U S A. 2002. PMID: 12441398 Free PMC article.

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