Levine B - Search Results

1

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene.

Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A, Rosen J, Eskelinen EL, Mizushima N, Ohsumi Y, Cattoretti G, Levine B. Qu X, et al. Among authors: levine b. J Clin Invest. 2003 Dec;112(12):1809-20. doi: 10.1172/JCI20039. Epub 2003 Nov 24. J Clin Invest. 2003. PMID: 14638851 Free PMC article.

2

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.

Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B. Pattingre S, et al. Among authors: levine b. Cell. 2005 Sep 23;122(6):927-39. doi: 10.1016/j.cell.2005.07.002. Cell. 2005. PMID: 16179260 Free article.

3

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function.

Furuya N, Yu J, Byfield M, Pattingre S, Levine B. Furuya N, et al. Among authors: levine b. Autophagy. 2005 Apr;1(1):46-52. doi: 10.4161/auto.1.1.1542. Epub 2005 Apr 17. Autophagy. 2005. PMID: 16874027

4

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway.

Tallóczy Z, Jiang W, Virgin HW 4th, Leib DA, Scheuner D, Kaufman RJ, Eskelinen EL, Levine B. Tallóczy Z, et al. Among authors: levine b. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):190-5. doi: 10.1073/pnas.012485299. Epub 2001 Dec 26. Proc Natl Acad Sci U S A. 2002. PMID: 11756670 Free PMC article.

5

Autophagy genes are essential for dauer development and life-span extension in C. elegans.

Meléndez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Meléndez A, et al. Among authors: levine b. Science. 2003 Sep 5;301(5638):1387-91. doi: 10.1126/science.1087782. Science. 2003. PMID: 12958363

6

Induction of autophagy and inhibition of tumorigenesis by beclin 1.

Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. Liang XH, et al. Among authors: levine b. Nature. 1999 Dec 9;402(6762):672-6. doi: 10.1038/45257. Nature. 1999. PMID: 10604474

7

Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function.

Liang XH, Yu J, Brown K, Levine B. Liang XH, et al. Among authors: levine b. Cancer Res. 2001 Apr 15;61(8):3443-9. Cancer Res. 2001. PMID: 11309306

8

Autophagy in mammalian development and differentiation.

Mizushima N, Levine B. Mizushima N, et al. Among authors: levine b. Nat Cell Biol. 2010 Sep;12(9):823-30. doi: 10.1038/ncb0910-823. Nat Cell Biol. 2010. PMID: 20811354 Free PMC article. Review.

9

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.

Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, White M, Reichelt J, Levine B. Wang RC, et al. Among authors: levine b. Science. 2012 Nov 16;338(6109):956-9. doi: 10.1126/science.1225967. Epub 2012 Oct 25. Science. 2012. PMID: 23112296 Free PMC article.

10

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Fernández ÁF, Sebti S, Wei Y, Zou Z, Shi M, McMillan KL, He C, Ting T, Liu Y, Chiang WC, Marciano DK, Schiattarella GG, Bhagat G, Moe OW, Hu MC, Levine B. Fernández ÁF, et al. Among authors: levine b. Nature. 2018 Jun;558(7708):136-140. doi: 10.1038/s41586-018-0162-7. Epub 2018 May 30. Nature. 2018. PMID: 29849149 Free PMC article.

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