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Page 1
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Agrelo R, Cheng WH, Setien F, Ropero S, Espada J, Fraga MF, Herranz M, Paz MF, Sanchez-Cespedes M, Artiga MJ, Guerrero D, Castells A, von Kobbe C, Bohr VA, Esteller M. Agrelo R, et al. Among authors: espada j. Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8822-7. doi: 10.1073/pnas.0600645103. Epub 2006 May 24. Proc Natl Acad Sci U S A. 2006. PMID: 16723399 Free PMC article.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Fraga MF, et al. Among authors: espada j. Nat Genet. 2005 Apr;37(4):391-400. doi: 10.1038/ng1531. Epub 2005 Mar 13. Nat Genet. 2005. PMID: 15765097
Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.
Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Pérez-Rosado A, Sanchez-Aguilera A, Fraga MF, Piris MA, Esteller M. Agrelo R, et al. Among authors: espada j. J Clin Oncol. 2005 Jun 10;23(17):3940-7. doi: 10.1200/JCO.2005.11.650. Epub 2005 May 2. J Clin Oncol. 2005. PMID: 15867203
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells.
Espada J, Ballestar E, Santoro R, Fraga MF, Villar-Garea A, Németh A, Lopez-Serra L, Ropero S, Aranda A, Orozco H, Moreno V, Juarranz A, Stockert JC, Längst G, Grummt I, Bickmore W, Esteller M. Espada J, et al. Nucleic Acids Res. 2007;35(7):2191-8. doi: 10.1093/nar/gkm118. Epub 2007 Mar 13. Nucleic Acids Res. 2007. PMID: 17355984 Free PMC article.
206 results