Ireton GC - Search Results

1

Design of a novel globular protein fold with atomic-level accuracy.

Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Kuhlman B, et al. Among authors: ireton gc. Science. 2003 Nov 21;302(5649):1364-8. doi: 10.1126/science.1089427. Science. 2003. PMID: 14631033

2

The structure of Escherichia coli cytosine deaminase.

Ireton GC, McDermott G, Black ME, Stoddard BL. Ireton GC, et al. J Mol Biol. 2002 Jan 25;315(4):687-97. doi: 10.1006/jmbi.2001.5277. J Mol Biol. 2002. PMID: 11812140

3

The 1.14 A crystal structure of yeast cytosine deaminase: evolution of nucleotide salvage enzymes and implications for genetic chemotherapy.

Ireton GC, Black ME, Stoddard BL. Ireton GC, et al. Structure. 2003 Aug;11(8):961-72. doi: 10.1016/s0969-2126(03)00153-9. Structure. 2003. PMID: 12906827 Free article.

4

Microseed matrix screening to improve crystals of yeast cytosine deaminase.

Ireton GC, Stoddard BL. Ireton GC, et al. Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):601-5. doi: 10.1107/S0907444903029664. Epub 2004 Feb 25. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 14993707

5

Crystallization and preliminary X-ray analysis of bacterial cytosine deaminase.

Ireton GC, Black ME, Stoddard BL. Ireton GC, et al. Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1643-5. doi: 10.1107/s0907444901011064. Epub 2001 Oct 25. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11679731

6

Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy.

Mahan SD, Ireton GC, Knoeber C, Stoddard BL, Black ME. Mahan SD, et al. Among authors: ireton gc. Protein Eng Des Sel. 2004 Aug;17(8):625-33. doi: 10.1093/protein/gzh074. Epub 2004 Sep 20. Protein Eng Des Sel. 2004. PMID: 15381761

7

Alanine-scanning mutagenesis reveals a cytosine deaminase mutant with altered substrate preference.

Mahan SD, Ireton GC, Stoddard BL, Black ME. Mahan SD, et al. Among authors: ireton gc. Biochemistry. 2004 Jul 20;43(28):8957-64. doi: 10.1021/bi049720z. Biochemistry. 2004. PMID: 15248753

8

Biochemical and biophysical analyses of recombinant forms of human topoisomerase I.

Stewart L, Ireton GC, Parker LH, Madden KR, Champoux JJ. Stewart L, et al. Among authors: ireton gc. J Biol Chem. 1996 Mar 29;271(13):7593-601. doi: 10.1074/jbc.271.13.7593. J Biol Chem. 1996. PMID: 8631793 Free article.

9

A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay.

Stewart L, Ireton GC, Champoux JJ. Stewart L, et al. Among authors: ireton gc. J Biol Chem. 1999 Nov 12;274(46):32950-60. doi: 10.1074/jbc.274.46.32950. J Biol Chem. 1999. PMID: 10551862 Free article.

10

Expression of human topoisomerase I with a partial deletion of the linker region yields monomeric and dimeric enzymes that respond differently to camptothecin.

Ireton GC, Stewart L, Parker LH, Champoux JJ. Ireton GC, et al. J Biol Chem. 2000 Aug 18;275(33):25820-30. doi: 10.1074/jbc.M002144200. J Biol Chem. 2000. PMID: 10827183 Free article.

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