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A novel targeted T-cell modulator, efalizumab, for plaque psoriasis.
Lebwohl M, Tyring SK, Hamilton TK, Toth D, Glazer S, Tawfik NH, Walicke P, Dummer W, Wang X, Garovoy MR, Pariser D; Efalizumab Study Group. Lebwohl M, et al. Among authors: garovoy mr. N Engl J Med. 2003 Nov 20;349(21):2004-13. doi: 10.1056/NEJMoa030002. N Engl J Med. 2003. PMID: 14627785 Free article. Clinical Trial.
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, Krueger JG. Lowes MA, et al. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19057-62. doi: 10.1073/pnas.0509736102. Proc Natl Acad Sci U S A. 2005. PMID: 16380428 Free PMC article.
The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody.
Papp K, Bissonnette R, Krueger JG, Carey W, Gratton D, Gulliver WP, Lui H, Lynde CW, Magee A, Minier D, Ouellet JP, Patel P, Shapiro J, Shear NH, Kramer S, Walicke P, Bauer R, Dedrick RL, Kim SS, White M, Garovoy MR. Papp K, et al. Among authors: garovoy mr. J Am Acad Dermatol. 2001 Nov;45(5):665-74. doi: 10.1067/mjd.2001.117850. J Am Acad Dermatol. 2001. PMID: 11606914 Clinical Trial.
157 results