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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.
Veazey RS, Klasse PJ, Ketas TJ, Reeves JD, Piatak M Jr, Kunstman K, Kuhmann SE, Marx PA, Lifson JD, Dufour J, Mefford M, Pandrea I, Wolinsky SM, Doms RW, DeMartino JA, Siciliano SJ, Lyons K, Springer MS, Moore JP. Veazey RS, et al. Among authors: lyons k. J Exp Med. 2003 Nov 17;198(10):1551-62. doi: 10.1084/jem.20031266. J Exp Med. 2003. PMID: 14623909 Free PMC article.
Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 2: Discovery of potent, selective, and orally bioavailable compounds.
Shen DM, Shu M, Willoughby CA, Shah S, Lynch CL, Hale JJ, Mills SG, Chapman KT, Malkowitz L, Springer MS, Gould SL, DeMartino JA, Siciliano SJ, Lyons K, Pivnichny JV, Kwei GY, Carella A, Carver G, Holmes K, Schleif WA, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller MD, Emini EA. Shen DM, et al. Among authors: lyons k. Bioorg Med Chem Lett. 2004 Feb 23;14(4):941-5. doi: 10.1016/j.bmcl.2003.12.005. Bioorg Med Chem Lett. 2004. PMID: 15012998
CCR5 blockade modulates inflammation and alloimmunity in primates.
Schröder C, Pierson RN 3rd, Nguyen BN, Kawka DW, Peterson LB, Wu G, Zhang T, Springer MS, Siciliano SJ, Iliff S, Ayala JM, Lu M, Mudgett JS, Lyons K, Mills SG, Miller GG, Singer II, Azimzadeh AM, DeMartino JA. Schröder C, et al. Among authors: lyons k. J Immunol. 2007 Aug 15;179(4):2289-99. doi: 10.4049/jimmunol.179.4.2289. J Immunol. 2007. PMID: 17675490
Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 3: SAR studies on the benzylpyrazole segment.
Shu M, Loebach JL, Parker KA, Mills SG, Chapman KT, Shen DM, Malkowitz L, Springer MS, Gould SL, DeMartino JA, Siciliano SJ, Salvo JD, Lyons K, Pivnichny JV, Kwei GY, Carella A, Carver G, Holmes K, Schleif WA, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller MD, Emini EA. Shu M, et al. Among authors: lyons k. Bioorg Med Chem Lett. 2004 Feb 23;14(4):947-52. doi: 10.1016/j.bmcl.2003.12.006. Bioorg Med Chem Lett. 2004. PMID: 15012999
Digital Dentists: A Curriculum for the 21st Century.
Mun M, Byrne S, Shaw L, Lyons K. Mun M, et al. Among authors: lyons k. JMIR Med Educ. 2025 Jan 8;11:e54153. doi: 10.2196/54153. JMIR Med Educ. 2025. PMID: 39789757 Free PMC article.
An Evaluation of Primary Care Clinician Referrals for Behavioral Weight Loss Counseling.
Saraiya VM, Berkowitz SA, Johnston LF, Couper DJ, Sotres-Alvarez D, Lyons KM, Thaxton CK, Skinner HG, Samuel-Hodge CD, Keyserling TC. Saraiya VM, et al. Among authors: lyons km. J Prim Care Community Health. 2024 Jan-Dec;15:21501319241308054. doi: 10.1177/21501319241308054. J Prim Care Community Health. 2024. PMID: 39690977 Free PMC article.
1,285 results