Ojima I - Search Results

1

Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

Brooks TA, Minderman H, O'Loughlin KL, Pera P, Ojima I, Baer MR, Bernacki RJ. Brooks TA, et al. Among authors: ojima i. Mol Cancer Ther. 2003 Nov;2(11):1195-205. Mol Cancer Ther. 2003. PMID: 14617793

2

Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

Ojima I, Park YH, Sun CM, Fenoglio I, Appendino G, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 1994 May 13;37(10):1408-10. doi: 10.1021/jm00036a004. J Med Chem. 1994. PMID: 8182698 No abstract available.

3

Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice.

Sharma A, Straubinger RM, Ojima I, Bernacki RJ. Sharma A, et al. Among authors: ojima i. J Pharm Sci. 1995 Dec;84(12):1400-4. doi: 10.1002/jps.2600841204. J Pharm Sci. 1995. PMID: 8748320

4

Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells.

Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 1996 Sep 27;39(20):3889-96. doi: 10.1021/jm9604080. J Med Chem. 1996. PMID: 8831755

5

Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.

Ojima I, Slater JC, Kuduk SD, Takeuchi CS, Gimi RH, Sun CM, Park YH, Pera P, Veith JM, Bernacki RJ. Ojima I, et al. J Med Chem. 1997 Jan 31;40(3):267-78. doi: 10.1021/jm960563e. J Med Chem. 1997. PMID: 9022793

6

Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity.

Ojima I, Kuduk SD, Pera P, Veith JM, Bernacki RJ. Ojima I, et al. J Med Chem. 1997 Jan 31;40(3):279-85. doi: 10.1021/jm9606711. J Med Chem. 1997. PMID: 9022794

7

New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells.

Ojima I, Bounaud PY, Takeuchi C, Pera P, Bernacki RJ. Ojima I, et al. Bioorg Med Chem Lett. 1998 Jan 20;8(2):189-94. doi: 10.1016/s0960-894x(97)10218-9. Bioorg Med Chem Lett. 1998. PMID: 9871652

8

Synthesis and structure-activity relationships of new second-generation taxoids.

Ojima I, Wang T, Miller ML, Lin S, Borella CP, Geng X, Pera P, Bernacki RJ. Ojima I, et al. Bioorg Med Chem Lett. 1999 Dec 20;9(24):3423-8. doi: 10.1016/s0960-894x(99)00629-0. Bioorg Med Chem Lett. 1999. PMID: 10617084

9

Syntheses and biological activity of C-3'-difluoromethyl-taxoids.

Ojima I, Lin S, Slater JC, Wang T, Pera P, Bernacki RJ, Ferlini C, Scambia G. Ojima I, et al. Bioorg Med Chem. 2000 Jul;8(7):1619-28. doi: 10.1016/s0968-0896(00)00093-6. Bioorg Med Chem. 2000. PMID: 10976509

10

Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors.

Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G. Ferlini C, et al. Among authors: ojima i. Br J Cancer. 2000 Dec;83(12):1762-8. doi: 10.1054/bjoc.2000.1500. Br J Cancer. 2000. PMID: 11104578 Free PMC article.

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