O'toole K - Search Results

1

Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor.

Yokoi A, McCrudden KW, Huang J, Kim ES, Soffer SZ, Frischer JS, Serur A, New T, Yuan J, Mansukhani M, O'toole K, Yamashiro DJ, Kandel JJ. Yokoi A, et al. J Pediatr Surg. 2003 Nov;38(11):1569-73. doi: 10.1016/s0022-3468(03)00562-1. J Pediatr Surg. 2003. PMID: 14614702

2

p53 accumulation in favorable-histology Wilms tumor is associated with angiogenesis and clinically aggressive disease.

Huang J, Soffer SZ, Kim ES, Yokoi A, Moore JT, McCrudden KW, Manley C, Middlesworth W, O'Toole K, Stolar C, Yamashiro DJ, Kandel JJ. Huang J, et al. J Pediatr Surg. 2002 Mar;37(3):523-7. doi: 10.1053/jpsu.2002.30858. J Pediatr Surg. 2002. PMID: 11877681

3

Resistance of a VEGF-producing tumor to anti-VEGF antibody: unimpeded growth of human rhabdoid tumor xenografts.

Soffer SZ, Kim E, Huang J, McCrudden K, Yokoi A, Moore JT, Manley C, O'Toole K, Middlesworth W, Stolar C, Yamashiro DJ, Kandel JJ. Soffer SZ, et al. J Pediatr Surg. 2002 Mar;37(3):528-32. doi: 10.1053/jpsu.2002.30859. J Pediatr Surg. 2002. PMID: 11877682

4

Topotecan is anti-angiogenic in experimental hepatoblastoma.

McCrudden KW, Yokoi A, Thosani A, Soffer SZ, Kim ES, Huang J, Manley C, O'toole K, Yamashiro DJ, Kandel JJ, Middlesworth W. McCrudden KW, et al. J Pediatr Surg. 2002 Jun;37(6):857-61. doi: 10.1053/jpsu.2002.32887. J Pediatr Surg. 2002. PMID: 12037749

5

Regression of established tumors and metastases by potent vascular endothelial growth factor blockade.

Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O'Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Huang J, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7785-90. doi: 10.1073/pnas.1432908100. Epub 2003 Jun 12. Proc Natl Acad Sci U S A. 2003. PMID: 12805568 Free PMC article.

6

Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor.

Yokoi A, McCrudden KW, Huang J, Kim ES, Soffer SZ, Frischer JS, Serur A, New T, Yuan J, Mansukhani M, O'Toole K, Yamashiro DJ, Kandel JJ. Yokoi A, et al. Oncol Rep. 2003 Sep-Oct;10(5):1271-4. Oncol Rep. 2003. PMID: 12883692

7

Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis.

Huang J, Soffer SZ, Kim ES, McCrudden KW, Huang J, New T, Manley CA, Middlesworth W, O'Toole K, Yamashiro DJ, Kandel JJ. Huang J, et al. Mol Cancer Res. 2004 Jan;2(1):36-42. Mol Cancer Res. 2004. PMID: 14757844

8

Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature.

Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O'Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Frischer JS, et al. Int J Oncol. 2004 Sep;25(3):549-53. Int J Oncol. 2004. PMID: 15289855

9

All angiogenesis is not the same: Distinct patterns of response to antiangiogenic therapy in experimental neuroblastoma and Wilms tumor.

Kim E, Moore J, Huang J, Soffer S, Manley CA, O'Toole K, Middlesworth W, Stolar CJ, Kandel JJ, Yamashiro DJ. Kim E, et al. J Pediatr Surg. 2001 Feb;36(2):287-90. doi: 10.1053/jpsu.2001.20691. J Pediatr Surg. 2001. PMID: 11172417

10

Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors.

Huang J, Moore J, Soffer S, Kim E, Rowe D, Manley CA, O'Toole K, Middlesworth W, Stolar C, Yamashiro D, Kandel J. Huang J, et al. J Pediatr Surg. 2001 Feb;36(2):357-61. doi: 10.1053/jpsu.2001.20716. J Pediatr Surg. 2001. PMID: 11172434

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