Minter RR - Search Results

1

Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.

Baker KP, Edwards BM, Main SH, Choi GH, Wager RE, Halpern WG, Lappin PB, Riccobene T, Abramian D, Sekut L, Sturm B, Poortman C, Minter RR, Dobson CL, Williams E, Carmen S, Smith R, Roschke V, Hilbert DM, Vaughan TJ, Albert VR. Baker KP, et al. Among authors: minter rr. Arthritis Rheum. 2003 Nov;48(11):3253-65. doi: 10.1002/art.11299. Arthritis Rheum. 2003. PMID: 14613291 Free article.

2

The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS.

Edwards BM, Barash SC, Main SH, Choi GH, Minter R, Ullrich S, Williams E, Du Fou L, Wilton J, Albert VR, Ruben SM, Vaughan TJ. Edwards BM, et al. J Mol Biol. 2003 Nov 14;334(1):103-18. doi: 10.1016/j.jmb.2003.09.054. J Mol Biol. 2003. PMID: 14596803

3

Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.

Dobson CL, Main S, Newton P, Chodorge M, Cadwallader K, Humphreys R, Albert V, Vaughan TJ, Minter RR, Edwards BM. Dobson CL, et al. Among authors: minter rr. MAbs. 2009 Nov-Dec;1(6):552-62. doi: 10.4161/mabs.1.6.10057. Epub 2009 Nov 11. MAbs. 2009. PMID: 20068388 Free PMC article.

4

Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.

Popovic B, Breed J, Rees DG, Gardener MJ, Vinall LM, Kemp B, Spooner J, Keen J, Minter R, Uddin F, Colice G, Wilkinson T, Vaughan T, May RD. Popovic B, et al. J Mol Biol. 2017 Jan 20;429(2):208-219. doi: 10.1016/j.jmb.2016.12.005. Epub 2016 Dec 9. J Mol Biol. 2017. PMID: 27956146 Free article.

5

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

MacGregor P, Gonzalez-Munoz AL, Jobe F, Taylor MC, Rust S, Sandercock AM, Macleod OJS, Van Bocxlaer K, Francisco AF, D'Hooge F, Tiberghien A, Barry CS, Howard P, Higgins MK, Vaughan TJ, Minter R, Carrington M. MacGregor P, et al. PLoS Negl Trop Dis. 2019 May 23;13(5):e0007373. doi: 10.1371/journal.pntd.0007373. eCollection 2019 May. PLoS Negl Trop Dis. 2019. PMID: 31120889 Free PMC article.

6

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TI, Sansom DM, Bowen MA, Minter RR, Jermutus L. Douthwaite J, et al. Among authors: minter rr. J Immunol. 2017 Jan 1;198(1):528-537. doi: 10.4049/jimmunol.1600682. Epub 2016 Nov 23. J Immunol. 2017. PMID: 27881707

7

Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency.

Schindler C, Collinson A, Matthews C, Pointon A, Jenkinson L, Minter RR, Vaughan TJ, Tigue NJ. Schindler C, et al. Among authors: minter rr. PLoS One. 2019 Mar 29;14(3):e0214545. doi: 10.1371/journal.pone.0214545. eCollection 2019. PLoS One. 2019. PMID: 30925190 Free PMC article.

8

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

Macleod OJS, Bart JM, MacGregor P, Peacock L, Savill NJ, Hester S, Ravel S, Sunter JD, Trevor C, Rust S, Vaughan TJ, Minter R, Mohammed S, Gibson W, Taylor MC, Higgins MK, Carrington M. Macleod OJS, et al. Nat Commun. 2020 Mar 12;11(1):1326. doi: 10.1038/s41467-020-15125-y. Nat Commun. 2020. PMID: 32165615 Free PMC article.

9

High affinity single-chain variable fragments are specific and versatile targeting motifs for extracellular vesicles.

Longatti A, Schindler C, Collinson A, Jenkinson L, Matthews C, Fitzpatrick L, Blundy M, Minter R, Vaughan T, Shaw M, Tigue N. Longatti A, et al. Nanoscale. 2018 Aug 7;10(29):14230-14244. doi: 10.1039/c8nr03970d. Epub 2018 Jul 16. Nanoscale. 2018. PMID: 30010165

10

Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.

Trevor CE, Gonzalez-Munoz AL, Macleod OJS, Woodcock PG, Rust S, Vaughan TJ, Garman EF, Minter R, Carrington M, Higgins MK. Trevor CE, et al. Nat Microbiol. 2019 Dec;4(12):2074-2081. doi: 10.1038/s41564-019-0589-0. Epub 2019 Oct 21. Nat Microbiol. 2019. PMID: 31636418 Free PMC article.

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