Halpern WG - Search Results

1

Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.

Baker KP, Edwards BM, Main SH, Choi GH, Wager RE, Halpern WG, Lappin PB, Riccobene T, Abramian D, Sekut L, Sturm B, Poortman C, Minter RR, Dobson CL, Williams E, Carmen S, Smith R, Roschke V, Hilbert DM, Vaughan TJ, Albert VR. Baker KP, et al. Among authors: halpern wg. Arthritis Rheum. 2003 Nov;48(11):3253-65. doi: 10.1002/art.11299. Arthritis Rheum. 2003. PMID: 14613291 Free article.

2

Chronic administration of belimumab, a BLyS antagonist, decreases tissue and peripheral blood B-lymphocyte populations in cynomolgus monkeys: pharmacokinetic, pharmacodynamic, and toxicologic effects.

Halpern WG, Lappin P, Zanardi T, Cai W, Corcoran M, Zhong J, Baker KP. Halpern WG, et al. Toxicol Sci. 2006 Jun;91(2):586-99. doi: 10.1093/toxsci/kfj148. Epub 2006 Mar 3. Toxicol Sci. 2006. PMID: 16517838

3

Albugranin, a recombinant human granulocyte colony stimulating factor (G-CSF) genetically fused to recombinant human albumin induces prolonged myelopoietic effects in mice and monkeys.

Halpern W, Riccobene TA, Agostini H, Baker K, Stolow D, Gu ML, Hirsch J, Mahoney A, Carrell J, Boyd E, Grzegorzewski KJ. Halpern W, et al. Pharm Res. 2002 Nov;19(11):1720-9. doi: 10.1023/a:1020917732218. Pharm Res. 2002. PMID: 12458679

4

Pharmacokinetics and in vitro and in vivo anti-tumor response of an interleukin-2-human serum albumin fusion protein in mice.

Melder RJ, Osborn BL, Riccobene T, Kanakaraj P, Wei P, Chen G, Stolow D, Halpern WG, Migone TS, Wang Q, Grzegorzewski KJ, Gallant G. Melder RJ, et al. Among authors: halpern wg. Cancer Immunol Immunother. 2005 Jun;54(6):535-47. doi: 10.1007/s00262-004-0624-7. Epub 2004 Dec 8. Cancer Immunol Immunother. 2005. PMID: 15592670 Free PMC article.

5

Osteostat/tumor necrosis factor superfamily 18 inhibits osteoclastogenesis and is selectively expressed by vascular endothelial cells.

Nardelli B, Zaritskaya L, McAuliffe W, Ni Y, Lincoln C, Cho YH, Birse CE, Halpern W, Ullrich S, Moore PA. Nardelli B, et al. Endocrinology. 2006 Jan;147(1):70-8. doi: 10.1210/en.2005-0518. Epub 2005 Sep 22. Endocrinology. 2006. PMID: 16179414

6

Trail receptors: targets for cancer therapy.

Humphreys RC, Halpern W. Humphreys RC, et al. Adv Exp Med Biol. 2008;615:127-58. doi: 10.1007/978-1-4020-6554-5_7. Adv Exp Med Biol. 2008. PMID: 18437894 Review.

7

Placental and Fetal Effects of Onartuzumab, a Met/HGF Signaling Antagonist, When Administered to Pregnant Cynomolgus Monkeys.

Prell RA, Dybdal N, Arima A, Chihaya Y, Nijem I, Halpern W. Prell RA, et al. Toxicol Sci. 2018 Sep 1;165(1):186-197. doi: 10.1093/toxsci/kfy141. Toxicol Sci. 2018. PMID: 29893934

8

Combined administration of RG7652, a recombinant human monoclonal antibody against PCSK9, and atorvastatin does not result in reduction of immune function.

Gelzleichter TR, Halpern W, Erwin R, Baruch A, Leabman M, Forrest AS, Satterwhite CM, Peng K, Chilton J, Stevens D. Gelzleichter TR, et al. Toxicol Sci. 2014 Aug 1;140(2):470-80. doi: 10.1093/toxsci/kfu093. Epub 2014 May 20. Toxicol Sci. 2014. PMID: 24848798

9

Nonclinical toxicology development of a novel antibody antibiotic conjugate for treating invasive Staphylococcus Aureus infections.

Stagg NJ, Katavolos P, Achilles Poon K, Zhong S, Ljumanovic N, Kamath A, Cai H, Carrasco-Triguero M, Halpern W. Stagg NJ, et al. Toxicol Appl Pharmacol. 2022 Jan 15;435:115811. doi: 10.1016/j.taap.2021.115811. Epub 2021 Dec 9. Toxicol Appl Pharmacol. 2022. PMID: 34896194

10

In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection.

Rao GK, Prell RA, Laing ST, Burleson SCM, Nguyen A, McBride JM, Zhang C, Sheinson D, Halpern WG. Rao GK, et al. Among authors: halpern wg. Toxicol Sci. 2019 Jun 1;169(2):409-421. doi: 10.1093/toxsci/kfz053. Toxicol Sci. 2019. PMID: 30796434

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