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Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Lehr HA, Oesch F, Hengstler JG. Schiffer IB, et al. Among authors: heimerdinger ck. Cancer Res. 2003 Nov 1;63(21):7221-31. Cancer Res. 2003. PMID: 14612517
4-Epidoxycycline: an alternative to doxycycline to control gene expression in conditional mouse models.
Eger K, Hermes M, Uhlemann K, Rodewald S, Ortwein J, Brulport M, Bauer AW, Schormann W, Lupatsch F, Schiffer IB, Heimerdinger CK, Gebhard S, Spangenberg C, Prawitt D, Trost T, Zabel B, Sauer C, Tanner B, Kolbl H, Krugel U, Franke H, Illes P, Madaj-Sterba P, Bockamp EO, Beckers T, Hengstler JG. Eger K, et al. Among authors: heimerdinger ck. Biochem Biophys Res Commun. 2004 Oct 22;323(3):979-86. doi: 10.1016/j.bbrc.2004.08.187. Biochem Biophys Res Commun. 2004. PMID: 15381096