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A Cross-Species Atlas of the Dorsal Vagal Complex Reveals Neural Mediators of Cagrilintide's Effects on Energy Balance.
Ludwig MQ, Coester B, Gordian D, Hassan S, Tomlinson AJ, Toure MH, Christensen OP, Moltke-Prehn A, Brown JM, Rausch DM, Gowda A, Wu I, Kernodle S, Dong V, Ayensu-Mensah M, Sabatini PV, Shin JH, Kirigiti M, Egerod KL, Le Foll C, Lundh S, Gerstenberg MK, Lutz TA, Kievit P, Secher A, Raun K, Myers MG Jr, Pers TH. Ludwig MQ, et al. Among authors: myers mg jr. bioRxiv [Preprint]. 2025 Jan 15:2025.01.13.632726. doi: 10.1101/2025.01.13.632726. bioRxiv. 2025. PMID: 39868309 Free PMC article. Preprint.
Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP.
Wang Y, Qiu W, Kernodle S, Parker C, Padilla MA, Su J, Tomlinson AJ, Oldham S, Field J, Bernard E, Hornigold D, Rhodes CJ, Olson DP, Seeley RJ, Myers MG Jr. Wang Y, et al. Among authors: myers mg jr. Mol Metab. 2025 Jan 2;92:102093. doi: 10.1016/j.molmet.2024.102093. Online ahead of print. Mol Metab. 2025. PMID: 39755369 Free PMC article.
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist.
Polex-Wolf J, Deibler K, Hogendorf WFJ, Bau S, Glendorf T, Stidsen CE, Tornøe CW, Tiantang D, Lundh S, Pyke C, Tomlinson AJ, Kernodle S, Magrisso IJ, Conde-Frieboes KW, Myers MG Jr, Knudsen LB, Seeley RJ. Polex-Wolf J, et al. Among authors: myers mg jr. Sci Transl Med. 2024 Dec 4;16(776):eadk4908. doi: 10.1126/scitranslmed.adk4908. Epub 2024 Dec 4. Sci Transl Med. 2024. PMID: 39630884
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Among authors: myers mg jr. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. Nature. 2024. PMID: 39537932 Free PMC article.
Control of Physiologic Glucose Homeostasis via the Hypothalamic Modulation of Gluconeogenic Substrate Availability.
Hashsham A, Kodur N, Su J, Tomlinson AJ, Yacawych WT, Flak JN, Lewis KT, Oles LR, Mori H, Bozadjieva-Kramer N, Turcu AF, MacDougald OA, Myers MG Jr, Affinati AH. Hashsham A, et al. Among authors: myers mg jr. bioRxiv [Preprint]. 2024 May 21:2024.05.20.594873. doi: 10.1101/2024.05.20.594873. bioRxiv. 2024. PMID: 38826340 Free PMC article. Preprint.
Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice.
de Miera CS, Bellefontaine N, Allen SJ, Myers MG Jr, Elias CF. de Miera CS, et al. Among authors: myers mg jr. bioRxiv [Preprint]. 2024 Mar 22:2023.09.21.558865. doi: 10.1101/2023.09.21.558865. bioRxiv. 2024. Update in: Elife. 2024 Jul 15;13:RP93204. doi: 10.7554/eLife.93204. PMID: 37790549 Free PMC article. Updated. Preprint.
Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models.
Rupp AC, Tomlinson AJ, Affinati AH, Yacawych WT, Duensing AM, True C, Lindsley SR, Kirigiti MA, MacKenzie A, Polex-Wolf J, Li C, Knudsen LB, Seeley RJ, Olson DP, Kievit P, Myers MG Jr. Rupp AC, et al. Among authors: myers mg jr. J Clin Invest. 2023 Oct 2;133(19):e157515. doi: 10.1172/JCI157515. J Clin Invest. 2023. PMID: 37581939 Free PMC article.
231 results