Eeckhoute J - Search Results

1

Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity.

Eeckhoute J, Oxombre B, Formstecher P, Lefebvre P, Laine B. Eeckhoute J, et al. Nucleic Acids Res. 2003 Nov 15;31(22):6640-50. doi: 10.1093/nar/gkg850. Nucleic Acids Res. 2003. PMID: 14602925 Free PMC article.

2

Hematopoietic Somatic Mosaicism Is Associated With an Increased Risk of Postoperative Atrial Fibrillation.

Ninni S, Dombrowicz D, Kuznetsova T, Vicario R, Gao V, Molendi-Coste O, Haas J, Woitrain E, Coisne A, Neele AE, Prange K, Willemsen L, Aghezzaf S, Fragkogianni S, Tazibet A, Pineau L, White JR, Eeckhoute J, Koussa M, Dubrulle H, Juthier F, Soquet J, Vincentelli A, Edme JL, de Winther M, Geissmann F, Staels B, Montaigne D. Ninni S, et al. Among authors: eeckhoute j. J Am Coll Cardiol. 2023 Apr 4;81(13):1263-1278. doi: 10.1016/j.jacc.2023.01.036. J Am Coll Cardiol. 2023. PMID: 36990546 Free PMC article.

3

Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.

Laine B, Eeckhoute J, Suaud L, Briche I, Furuta H, Bell GI, Formstecher P. Laine B, et al. Among authors: eeckhoute j. FEBS Lett. 2000 Aug 11;479(1-2):41-5. doi: 10.1016/s0014-5793(00)01864-0. FEBS Lett. 2000. PMID: 10940385 Free article.

4

Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator.

Eeckhoute J, Formstecher P, Laine B. Eeckhoute J, et al. Mol Endocrinol. 2001 Jul;15(7):1200-10. doi: 10.1210/mend.15.7.0670. Mol Endocrinol. 2001. PMID: 11435618

5

Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells.

Oxombre B, Moerman E, Eeckhoute J, Formstecher P, Laine B. Oxombre B, et al. Among authors: eeckhoute j. J Mol Med (Berl). 2002 Jul;80(7):423-30. doi: 10.1007/s00109-002-0340-8. Epub 2002 May 8. J Mol Med (Berl). 2002. PMID: 12110948

6

Hepatocyte nuclear factor 4 alpha isoforms originated from the P1 promoter are expressed in human pancreatic beta-cells and exhibit stronger transcriptional potentials than P2 promoter-driven isoforms.

Eeckhoute J, Moerman E, Bouckenooghe T, Lukoviak B, Pattou F, Formstecher P, Kerr-Conte J, Vandewalle B, Laine B. Eeckhoute J, et al. Endocrinology. 2003 May;144(5):1686-94. doi: 10.1210/en.2002-0024. Endocrinology. 2003. PMID: 12697672

7

Hepatocyte nuclear factor 4alpha enhances the hepatocyte nuclear factor 1alpha-mediated activation of transcription.

Eeckhoute J, Formstecher P, Laine B. Eeckhoute J, et al. Nucleic Acids Res. 2004 May 11;32(8):2586-93. doi: 10.1093/nar/gkh581. Print 2004. Nucleic Acids Res. 2004. PMID: 15141028 Free PMC article.

8

Hepatocyte nuclear factor 4 alpha ligand binding and F domains mediate interaction and transcriptional synergy with the pancreatic islet LIM HD transcription factor Isl1.

Eeckhoute J, Briche I, Kurowska M, Formstecher P, Laine B. Eeckhoute J, et al. J Mol Biol. 2006 Dec 8;364(4):567-81. doi: 10.1016/j.jmb.2006.07.096. Epub 2006 Sep 12. J Mol Biol. 2006. PMID: 17022998

9

Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages.

Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B, Noel B, Eeckhoute J, Lefebvre P, Seckl JR, Staels B. Chinetti-Gbaguidi G, et al. Among authors: eeckhoute j. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):677-85. doi: 10.1161/ATVBAHA.111.241364. Epub 2011 Dec 29. Arterioscler Thromb Vasc Biol. 2012. PMID: 22207732 Free PMC article.

10

The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells.

Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F, Vandewalle B, Moerman E, Gmyr V, Kerr-Conte J, Eeckhoute J, Staels B, Lefebvre P. Briand O, et al. Among authors: eeckhoute j. Mol Endocrinol. 2012 Mar;26(3):399-413. doi: 10.1210/me.2011-1317. Epub 2012 Feb 2. Mol Endocrinol. 2012. PMID: 22301783 Free PMC article.

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