van Aalten DM - Search Results

1

Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone.

Vaaje-Kolstad G, Vasella A, Peter MG, Netter C, Houston DR, Westereng B, Synstad B, Eijsink VG, van Aalten DM. Vaaje-Kolstad G, et al. Among authors: van aalten dm. J Biol Chem. 2004 Jan 30;279(5):3612-9. doi: 10.1074/jbc.M310057200. Epub 2003 Nov 3. J Biol Chem. 2004. PMID: 14597613 Free article.

2

Structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 A resolution.

Kolstad G, Synstad B, Eijsink VG, van Aalten DM. Kolstad G, et al. Among authors: van aalten dm. Acta Crystallogr D Biol Crystallogr. 2002 Feb;58(Pt 2):377-9. doi: 10.1107/s0907444901018972. Epub 2002 Jan 24. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11807282

3

Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase.

Synstad B, Gåseidnes S, Van Aalten DM, Vriend G, Nielsen JE, Eijsink VG. Synstad B, et al. Among authors: van aalten dm. Eur J Biochem. 2004 Jan;271(2):253-62. doi: 10.1046/j.1432-1033.2003.03923.x. Eur J Biochem. 2004. PMID: 14717693 Free article.

4

Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin.

Vaaje-Kolstad G, Houston DR, Rao FV, Peter MG, Synstad B, van Aalten DM, Eijsink VG. Vaaje-Kolstad G, et al. Among authors: van aalten dm. Biochim Biophys Acta. 2004 Jan 14;1696(1):103-11. doi: 10.1016/j.bbapap.2003.09.014. Biochim Biophys Acta. 2004. PMID: 14726210

5

Structure-based exploration of cyclic dipeptide chitinase inhibitors.

Houston DR, Synstad B, Eijsink VG, Stark MJ, Eggleston IM, van Aalten DM. Houston DR, et al. Among authors: van aalten dm. J Med Chem. 2004 Nov 4;47(23):5713-20. doi: 10.1021/jm049940a. J Med Chem. 2004. PMID: 15509170 Free article.

6

Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21.

Vaaje-Kolstad G, Houston DR, Riemen AH, Eijsink VG, van Aalten DM. Vaaje-Kolstad G, et al. Among authors: van aalten dm. J Biol Chem. 2005 Mar 25;280(12):11313-9. doi: 10.1074/jbc.M407175200. Epub 2004 Dec 8. J Biol Chem. 2005. PMID: 15590674 Free article.

7

The non-catalytic chitin-binding protein CBP21 from Serratia marcescens is essential for chitin degradation.

Vaaje-Kolstad G, Horn SJ, van Aalten DM, Synstad B, Eijsink VG. Vaaje-Kolstad G, et al. Among authors: van aalten dm. J Biol Chem. 2005 Aug 5;280(31):28492-7. doi: 10.1074/jbc.M504468200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15929981 Free article.

8

Psammaplin A, a chitinase inhibitor isolated from the Fijian marine sponge Aplysinella rhax.

Tabudravu JN, Eijsink VG, Gooday GW, Jaspars M, Komander D, Legg M, Synstad B, van Aalten DM. Tabudravu JN, et al. Among authors: van aalten dm. Bioorg Med Chem. 2002 Apr;10(4):1123-8. doi: 10.1016/s0968-0896(01)00372-8. Bioorg Med Chem. 2002. PMID: 11836123

9

Crystal structures of allosamidin derivatives in complex with human macrophage chitinase.

Rao FV, Houston DR, Boot RG, Aerts JM, Sakuda S, van Aalten DM. Rao FV, et al. Among authors: van aalten dm. J Biol Chem. 2003 May 30;278(22):20110-6. doi: 10.1074/jbc.M300362200. Epub 2003 Mar 14. J Biol Chem. 2003. PMID: 12639956 Free article.

10

Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes.

Houston DR, Recklies AD, Krupa JC, van Aalten DM. Houston DR, et al. Among authors: van aalten dm. J Biol Chem. 2003 Aug 8;278(32):30206-12. doi: 10.1074/jbc.M303371200. Epub 2003 May 29. J Biol Chem. 2003. PMID: 12775711 Free article.

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