Blaskovich MA - Search Results

1

The development of protein farnesyltransferase inhibitors as signaling-based anticancer agents.

Ohkanda J, Blaskovich MA, Sebti SM, Hamilton AD. Ohkanda J, et al. Among authors: blaskovich ma. Prog Cell Cycle Res. 2003;5:211-7. Prog Cell Cycle Res. 2003. PMID: 14593715 Review.

2

Inhibitors of protein farnesyltransferase as novel anticancer agents.

Ohkanda J, Knowles DB, Blaskovich MA, Sebti SM, Hamilton AD. Ohkanda J, et al. Among authors: blaskovich ma. Curr Top Med Chem. 2002 Mar;2(3):303-23. doi: 10.2174/1568026023394281. Curr Top Med Chem. 2002. PMID: 11944822 Review.

3

Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine.

Sun J, Blaskovich MA, Knowles D, Qian Y, Ohkanda J, Bailey RD, Hamilton AD, Sebti SM. Sun J, et al. Among authors: blaskovich ma. Cancer Res. 1999 Oct 1;59(19):4919-26. Cancer Res. 1999. PMID: 10519405

4

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

Delarue FL, Adnane J, Joshi B, Blaskovich MA, Wang DA, Hawker J, Bizouarn F, Ohkanda J, Zhu K, Hamilton AD, Chellappan S, Sebti SM. Delarue FL, et al. Among authors: blaskovich ma. Oncogene. 2007 Feb 1;26(5):633-40. doi: 10.1038/sj.onc.1209819. Epub 2006 Aug 14. Oncogene. 2007. PMID: 16909123

5

Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I.

Peng H, Carrico D, Thai V, Blaskovich M, Bucher C, Pusateri EE, Sebti SM, Hamilton AD. Peng H, et al. Org Biomol Chem. 2006 May 7;4(9):1768-84. doi: 10.1039/b517572k. Epub 2006 Mar 21. Org Biomol Chem. 2006. PMID: 16633570

6

Design and synthesis of potent nonpeptidic farnesyltransferase inhibitors based on a terphenyl scaffold.

Ohkanda J, Lockman JW, Kothare MA, Qian Y, Blaskovich MA, Sebti SM, Hamilton AD. Ohkanda J, et al. Among authors: blaskovich ma. J Med Chem. 2002 Jan 3;45(1):177-88. doi: 10.1021/jm0103099. J Med Chem. 2002. PMID: 11754590

7

Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM. Blaskovich MA, et al. Cancer Res. 2003 Mar 15;63(6):1270-9. Cancer Res. 2003. PMID: 12649187

8

Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor.

Sun J, Blaskovich MA, Jain RK, Delarue F, Paris D, Brem S, Wotoczek-Obadia M, Lin Q, Coppola D, Choi K, Mullan M, Hamilton AD, Sebti SM. Sun J, et al. Among authors: blaskovich ma. Cancer Res. 2004 May 15;64(10):3586-92. doi: 10.1158/0008-5472.CAN-03-2673. Cancer Res. 2004. PMID: 15150116

9

In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability.

Carrico D, Ohkanda J, Kendrick H, Yokoyama K, Blaskovich MA, Bucher CJ, Buckner FS, Van Voorhis WC, Chakrabarti D, Croft SL, Gelb MH, Sebti SM, Hamilton AD. Carrico D, et al. Among authors: blaskovich ma. Bioorg Med Chem. 2004 Dec 15;12(24):6517-26. doi: 10.1016/j.bmc.2004.09.020. Bioorg Med Chem. 2004. PMID: 15556768

10

Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-I.

Carrico D, Blaskovich MA, Bucher CJ, Sebti SM, Hamilton AD. Carrico D, et al. Among authors: blaskovich ma. Bioorg Med Chem. 2005 Feb 1;13(3):677-88. doi: 10.1016/j.bmc.2004.10.053. Bioorg Med Chem. 2005. PMID: 15653335

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

174 results

Search Page

Filters