Mennerick SJ - Search Results

1

Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.

Darbandi-Tonkabon R, Manion BD, Hastings WR, Craigen WJ, Akk G, Bracamontes JR, He Y, Sheiko TV, Steinbach JH, Mennerick SJ, Covey DF, Evers AS. Darbandi-Tonkabon R, et al. Among authors: mennerick sj. J Pharmacol Exp Ther. 2004 Feb;308(2):502-11. doi: 10.1124/jpet.103.058123. Epub 2003 Oct 30. J Pharmacol Exp Ther. 2004. PMID: 14593090

2

Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures.

Zorumski CF, Mennerick SJ, Covey DF. Zorumski CF, et al. Among authors: mennerick sj. Synapse. 1998 Jun;29(2):162-71. doi: 10.1002/(SICI)1098-2396(199806)29:2<162::AID-SYN7>3.0.CO;2-5. Synapse. 1998. PMID: 9593106

3

Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors.

Shen W, Mennerick S, Zorumski EC, Covey DF, Zorumski CF. Shen W, et al. Neuropharmacology. 1999 Feb;38(2):267-71. doi: 10.1016/s0028-3908(98)00172-5. Neuropharmacology. 1999. PMID: 10218867

4

Slow death of postnatal hippocampal neurons by GABA(A) receptor overactivation.

Xu W, Cormier R, Fu T, Covey DF, Isenberg KE, Zorumski CF, Mennerick S. Xu W, et al. J Neurosci. 2000 May 1;20(9):3147-56. doi: 10.1523/JNEUROSCI.20-09-03147.2000. J Neurosci. 2000. PMID: 10777778 Free PMC article.

5

Pregnenolone sulfate modulates inhibitory synaptic transmission by enhancing GABA(A) receptor desensitization.

Shen W, Mennerick S, Covey DF, Zorumski CF. Shen W, et al. J Neurosci. 2000 May 15;20(10):3571-9. doi: 10.1523/JNEUROSCI.20-10-03571.2000. J Neurosci. 2000. PMID: 10804198 Free PMC article.

6

Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

Covey DF, Han M, Kumar AS, de La Cruz MA, Meadows ES, Hu Y, Tonnies A, Nathan D, Coleman M, Benz A, Evers AS, Zorumski CF, Mennerick S. Covey DF, et al. J Med Chem. 2000 Aug 24;43(17):3201-4. doi: 10.1021/jm0002477. J Med Chem. 2000. PMID: 10966737 No abstract available.

7

Potential clinical uses of neuroactive steroids.

Zorumski CF, Mennerick S, Isenberg KE, Covey DF. Zorumski CF, et al. Curr Opin Investig Drugs. 2000 Nov;1(3):360-9. Curr Opin Investig Drugs. 2000. PMID: 11249720 Review.

8

Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide.

Todorovic SM, Jevtovic-Todorovic V, Mennerick S, Perez-Reyes E, Zorumski CF. Todorovic SM, et al. Mol Pharmacol. 2001 Sep;60(3):603-10. Mol Pharmacol. 2001. PMID: 11502893

9

Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission.

Mennerick S, Zeng CM, Benz A, Shen W, Izumi Y, Evers AS, Covey DF, Zorumski CF. Mennerick S, et al. Mol Pharmacol. 2001 Oct;60(4):732-41. Mol Pharmacol. 2001. PMID: 11562435

10

Recent developments in structure-activity relationships for steroid modulators of GABA(A) receptors.

Covey DF, Evers AS, Mennerick S, Zorumski CF, Purdy RH. Covey DF, et al. Brain Res Brain Res Rev. 2001 Nov;37(1-3):91-7. doi: 10.1016/s0165-0173(01)00126-6. Brain Res Brain Res Rev. 2001. PMID: 11744077 Review.

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