Pearl LH - Search Results

1

Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs.

Boskovic J, Rivera-Calzada A, Maman JD, Chacón P, Willison KR, Pearl LH, Llorca O. Boskovic J, et al. Among authors: pearl lh. EMBO J. 2003 Nov 3;22(21):5875-82. doi: 10.1093/emboj/cdg555. EMBO J. 2003. PMID: 14592984 Free PMC article.

2

Crystal structure of a thwarted mismatch glycosylase DNA repair complex.

Barrett TE, Schärer OD, Savva R, Brown T, Jiricny J, Verdine GL, Pearl LH. Barrett TE, et al. Among authors: pearl lh. EMBO J. 1999 Dec 1;18(23):6599-609. doi: 10.1093/emboj/18.23.6599. EMBO J. 1999. PMID: 10581234 Free PMC article.

3

Backbone 1H, 13C, and 15N resonance assignments for the C-terminal region of Ku86 (Ku86CTR).

Harris R, Maman JD, Hinks JA, Sankar A, Pearl LH, Driscoll PC. Harris R, et al. Among authors: pearl lh. J Biomol NMR. 2002 Apr;22(4):373-4. doi: 10.1023/a:1014947206138. J Biomol NMR. 2002. PMID: 12018486 No abstract available.

4

Crystal structure of the CCTgamma apical domain: implications for substrate binding to the eukaryotic cytosolic chaperonin.

Pappenberger G, Wilsher JA, Roe SM, Counsell DJ, Willison KR, Pearl LH. Pappenberger G, et al. Among authors: pearl lh. J Mol Biol. 2002 May 17;318(5):1367-79. doi: 10.1016/s0022-2836(02)00190-0. J Mol Biol. 2002. PMID: 12083524

5

The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR).

Harris R, Esposito D, Sankar A, Maman JD, Hinks JA, Pearl LH, Driscoll PC. Harris R, et al. Among authors: pearl lh. J Mol Biol. 2004 Jan 9;335(2):573-82. doi: 10.1016/j.jmb.2003.10.047. J Mol Biol. 2004. PMID: 14672664

6

Electron microscopy studies on DNA recognition by DNA-PK.

Llorca O, Pearl LH. Llorca O, et al. Among authors: pearl lh. Micron. 2004;35(8):625-33. doi: 10.1016/j.micron.2004.05.004. Micron. 2004. PMID: 15288642 Review.

7

Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).

Rivera-Calzada A, Maman JD, Spagnolo L, Pearl LH, Llorca O. Rivera-Calzada A, et al. Among authors: pearl lh. Structure. 2005 Feb;13(2):243-55. doi: 10.1016/j.str.2004.12.006. Structure. 2005. PMID: 15698568 Free article.

8

Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair.

Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O. Spagnolo L, et al. Among authors: pearl lh. Mol Cell. 2006 May 19;22(4):511-9. doi: 10.1016/j.molcel.2006.04.013. Mol Cell. 2006. PMID: 16713581 Free article.

9

Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange.

Oliver AW, Paul A, Boxall KJ, Barrie SE, Aherne GW, Garrett MD, Mittnacht S, Pearl LH. Oliver AW, et al. Among authors: pearl lh. EMBO J. 2006 Jul 12;25(13):3179-90. doi: 10.1038/sj.emboj.7601209. Epub 2006 Jun 22. EMBO J. 2006. PMID: 16794575 Free PMC article.

10

Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs.

Rivera-Calzada A, Spagnolo L, Pearl LH, Llorca O. Rivera-Calzada A, et al. Among authors: pearl lh. EMBO Rep. 2007 Jan;8(1):56-62. doi: 10.1038/sj.embor.7400847. Epub 2006 Dec 8. EMBO Rep. 2007. PMID: 17159921 Free PMC article.

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