Van Wart HE - Search Results

1

Design and synthesis of orally active inhibitors of TNF synthesis as anti-rheumatoid arthritis drugs.

Chen JJ, Dewdney N, Lin X, Martin RL, Walker KA, Huang J, Chu F, Eugui E, Mirkovich A, Kim Y, Sarma K, Arzeno H, Van Wart HE. Chen JJ, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3951-4. doi: 10.1016/j.bmcl.2003.08.076. Bioorg Med Chem Lett. 2003. PMID: 14592482

2

Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-phase optimization of side chains.

Dankwardt SM, Abbot SC, Broka CA, Martin RL, Chan CS, Springman EB, Van Wart HE, Walker KA. Dankwardt SM, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1233-5. doi: 10.1016/s0960-894x(02)00117-8. Bioorg Med Chem Lett. 2002. PMID: 11934595

3

Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase.

Dankwardt SM, Billedeau RJ, Lawley LK, Abbot SC, Martin RL, Chan CS, Van Wart HE, Walker KA. Dankwardt SM, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2000 Nov 20;10(22):2513-6. doi: 10.1016/s0960-894x(00)00525-4. Bioorg Med Chem Lett. 2000. PMID: 11086718

4

Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase: solid-phase synthesis of ornithine analogues.

Dankwardt SM, Martin RL, Chan CS, Van Wart HE, Walker KA, Delaet NG, Robinson LA. Dankwardt SM, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2085-8. doi: 10.1016/s0960-894x(01)00384-5. Bioorg Med Chem Lett. 2001. PMID: 11514144

5

Novel inhibitors of procollagen C-terminal proteinase. Part 1: diamino Acid hydroxamates.

Delaet NG, Robinson LA, Wilson DM, Sullivan RW, Bradley EK, Dankwardt SM, Martin RL, Van Wart HE, Walker KA. Delaet NG, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2101-4. doi: 10.1016/s0960-894x(03)00404-9. Bioorg Med Chem Lett. 2003. PMID: 12798313

6

Novel inhibitors of procollagen C-proteinase. Part 2: glutamic acid hydroxamates.

Robinson LA, Wilson DM, Delaet NG, Bradley EK, Dankwardt SM, Campbell JA, Martin RL, Van Wart HE, Walker KA, Sullivan RW. Robinson LA, et al. Among authors: van wart he. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2381-4. doi: 10.1016/s0960-894x(03)00402-5. Bioorg Med Chem Lett. 2003. PMID: 12824039

7

Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors.

Lovejoy B, Welch AR, Carr S, Luong C, Broka C, Hendricks RT, Campbell JA, Walker KA, Martin R, Van Wart H, Browner MF. Lovejoy B, et al. Nat Struct Biol. 1999 Mar;6(3):217-21. doi: 10.1038/6657. Nat Struct Biol. 1999. PMID: 10074939

8

Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase.

Gronski TJ Jr, Martin RL, Kobayashi DK, Walsh BC, Holman MC, Huber M, Van Wart HE, Shapiro SD. Gronski TJ Jr, et al. Among authors: van wart he. J Biol Chem. 1997 May 2;272(18):12189-94. doi: 10.1074/jbc.272.18.12189. J Biol Chem. 1997. PMID: 9115292 Free article.

9

Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase.

Billinghurst RC, Wu W, Ionescu M, Reiner A, Dahlberg L, Chen J, van Wart H, Poole AR. Billinghurst RC, et al. Arthritis Rheum. 2000 Mar;43(3):664-72. doi: 10.1002/1529-0131(200003)43:3<664::AID-ANR24>3.0.CO;2-D. Arthritis Rheum. 2000. PMID: 10728761 Free article.

10

Purification of human matrilysin produced in Escherichia coli and characterization using a new optimized fluorogenic peptide substrate.

Welch AR, Holman CM, Browner MF, Gehring MR, Kan CC, Van Wart HE. Welch AR, et al. Among authors: van wart he. Arch Biochem Biophys. 1995 Dec 1;324(1):59-64. doi: 10.1006/abbi.1995.9929. Arch Biochem Biophys. 1995. PMID: 7503560

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