Auclair K - Search Results

1

Solution 1H, 15N NMR spectroscopic characterization of substrate-bound, cyanide-inhibited human heme oxygenase: water occupation of the distal cavity.

Li Y, Syvitski RT, Auclair K, Ortiz de Montellano P, La Mar GN. Li Y, et al. Among authors: auclair k. J Am Chem Soc. 2003 Nov 5;125(44):13392-403. doi: 10.1021/ja036176t. J Am Chem Soc. 2003. PMID: 14583035

2

Solution NMR characterization of an unusual distal H-bond network in the active site of the cyanide-inhibited, human heme oxygenase complex of the symmetric substrate, 2,4-dimethyldeuterohemin.

Li Y, Syvitski RT, Auclair K, Wilks A, Ortiz De Montellano PR, La Mar GN. Li Y, et al. Among authors: auclair k. J Biol Chem. 2002 Sep 6;277(36):33018-31. doi: 10.1074/jbc.M204216200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070167 Free article.

3

1H NMR detection of immobilized water molecules within a strong distal hydrogen-bonding network of substrate-bound human heme oxygenase-1.

Syvitski RT, Li Y, Auclair K, Ortiz De Montellano PR, La Mar GN. Syvitski RT, et al. Among authors: auclair k. J Am Chem Soc. 2002 Dec 4;124(48):14296-7. doi: 10.1021/ja028108x. J Am Chem Soc. 2002. PMID: 12452690

4

1H NMR investigation of the solution structure of substrate-free human heme oxygenase: comparison to the cyanide-inhibited, substrate-bound complex.

Li Y, Syvitski RT, Auclair K, de Montellano PR, La Mar GN. Li Y, et al. Among authors: auclair k. J Biol Chem. 2004 Mar 12;279(11):10195-205. doi: 10.1074/jbc.M308379200. Epub 2003 Dec 3. J Biol Chem. 2004. PMID: 14660632 Free article.

5

Solution 1H NMR of the active site of substrate-bound, cyanide-inhibited human heme oxygenase. comparison to the crystal structure of the water-ligated form.

La Mar GN, Asokan A, Espiritu B, Yeh DC, Auclair K, Ortiz De Montellano PR. La Mar GN, et al. Among authors: auclair k. J Biol Chem. 2001 May 11;276(19):15676-87. doi: 10.1074/jbc.M009974200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297521 Free article.

6

Roles of the proximal heme thiolate ligand in cytochrome p450(cam).

Auclair K, Moënne-Loccoz P, Ortiz de Montellano PR. Auclair K, et al. J Am Chem Soc. 2001 May 30;123(21):4877-85. doi: 10.1021/ja0040262. J Am Chem Soc. 2001. PMID: 11457314

7

Revisiting the mechanism of P450 enzymes with the radical clocks norcarane and spiro[2,5]octane.

Auclair K, Hu Z, Little DM, Ortiz De Montellano PR, Groves JT. Auclair K, et al. J Am Chem Soc. 2002 May 29;124(21):6020-7. doi: 10.1021/ja025608h. J Am Chem Soc. 2002. PMID: 12022835

8

Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae.

Auclair K, Huang HW, Moënne-Loccoz P, Ortiz de Montellano PR. Auclair K, et al. Protein Expr Purif. 2003 Apr;28(2):340-9. doi: 10.1016/s1046-5928(02)00699-x. Protein Expr Purif. 2003. PMID: 12699699

9

Predictable stereoselective and chemoselective hydroxylations and epoxidations with P450 3A4.

Larsen AT, May EM, Auclair K. Larsen AT, et al. Among authors: auclair k. J Am Chem Soc. 2011 May 25;133(20):7853-8. doi: 10.1021/ja200551y. Epub 2011 Apr 29. J Am Chem Soc. 2011. PMID: 21528858

10

Substrate-dependent switching of the allosteric binding mechanism of a dimeric enzyme.

Freiburger L, Miletti T, Zhu S, Baettig O, Berghuis A, Auclair K, Mittermaier A. Freiburger L, et al. Among authors: auclair k. Nat Chem Biol. 2014 Nov;10(11):937-42. doi: 10.1038/nchembio.1626. Epub 2014 Sep 14. Nat Chem Biol. 2014. PMID: 25218742

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