Bockx M - Search Results

1

Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes.

Lavrijsen K, van Houdt J, van Dyck D, Hendrickx J, Bockx M, Hurkmans R, Meuldermans W, Le Jeune L, Lauwers W, Heykants J. Lavrijsen K, et al. Among authors: bockx m. Xenobiotica. 1992 Jul;22(7):815-36. doi: 10.3109/00498259209053143. Xenobiotica. 1992. PMID: 1455902

2

Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans.

Lavrijsen K, Van Houdt J, Van Dyck D, Hendrickx J, Lauwers W, Hurkmans R, Bockx M, Janssen C, Meuldermans W, Heykants J. Lavrijsen K, et al. Among authors: bockx m. Drug Metab Dispos. 1990 Sep-Oct;18(5):704-10. Drug Metab Dispos. 1990. PMID: 1981724

3

Excretion and biotransformation of cisapride in dogs and humans after oral administration.

Meuldermans W, Van Peer A, Hendrickx J, Lauwers W, Swysen E, Bockx M, Woestenborghs R, Heykants J. Meuldermans W, et al. Among authors: bockx m. Drug Metab Dispos. 1988 May-Jun;16(3):403-9. Drug Metab Dispos. 1988. PMID: 2900732

4

Location of the hydroxyl functions in hydroxylated metabolites of nebivolol in different animal species and human subjects as determined by on-line high-performance liquid chromatography-diode-array detection.

Hendrickx J, Bockx M, Zwijsen C, Borgmans C, Mannens G, Meuldermans W, Heykants J. Hendrickx J, et al. Among authors: bockx m. J Chromatogr A. 1996 Apr 5;729(1-2):341-54. doi: 10.1016/0021-9673(95)01114-5. J Chromatogr A. 1996. PMID: 9004959

5

The absorption, metabolism, and excretion of the novel neuromodulator RWJ-333369 (1,2-ethanediol, [1-2-chlorophenyl]-, 2-carbamate, [S]-) in humans.

Mannens GS, Hendrickx J, Janssen CG, Chien S, Van Hoof B, Verhaeghe T, Kao M, Kelley MF, Goris I, Bockx M, Verreet B, Bialer M, Meuldermans W. Mannens GS, et al. Among authors: bockx m. Drug Metab Dispos. 2007 Apr;35(4):554-65. doi: 10.1124/dmd.106.011940. Epub 2006 Aug 25. Drug Metab Dispos. 2007. PMID: 16936066 Clinical Trial.

6

In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping.

Vermeir M, Hemeryck A, Cuyckens F, Francesch A, Bockx M, Van Houdt J, Steemans K, Mannens G, Avilés P, De Coster R. Vermeir M, et al. Among authors: bockx m. Biochem Pharmacol. 2009 May 15;77(10):1642-54. doi: 10.1016/j.bcp.2009.02.020. Epub 2009 Mar 10. Biochem Pharmacol. 2009. PMID: 19426702

7

Absorption, metabolism, and excretion of oral ¹⁴C radiolabeled ibrutinib: an open-label, phase I, single-dose study in healthy men.

Scheers E, Leclercq L, de Jong J, Bode N, Bockx M, Laenen A, Cuyckens F, Skee D, Murphy J, Sukbuntherng J, Mannens G. Scheers E, et al. Among authors: bockx m. Drug Metab Dispos. 2015 Feb;43(2):289-97. doi: 10.1124/dmd.114.060061. Epub 2014 Dec 8. Drug Metab Dispos. 2015. PMID: 25488930 Clinical Trial.

8

Identifying metabolite ions of peptide drugs in the presence of an in vivo matrix background.

Cuyckens F, Dillen L, Cools W, Bockx M, Vereyken L, de Vries R, Mortishire-Smith RJ. Cuyckens F, et al. Among authors: bockx m. Bioanalysis. 2012 Mar;4(5):595-604. doi: 10.4155/bio.11.333. Bioanalysis. 2012. PMID: 22409556

9

High volume injections of biological samples for sensitive metabolite profiling and quantitation.

Koppen V, Jones R, Bockx M, Cuyckens F. Koppen V, et al. Among authors: bockx m. J Chromatogr A. 2014 Dec 12;1372C:102-109. doi: 10.1016/j.chroma.2014.10.087. Epub 2014 Nov 1. J Chromatogr A. 2014. PMID: 25465008

10

Speciation analysis of bromine-containing drug metabolites in feces samples from a human in vivo study by means of HPLC/ICP-MS combined with on-line isotope dilution.

Meermann B, Bockx M, Laenen A, Van Looveren C, Cuyckens F, Vanhaecke F. Meermann B, et al. Among authors: bockx m. Anal Bioanal Chem. 2012 Jan;402(1):439-48. doi: 10.1007/s00216-011-5339-y. Epub 2011 Aug 30. Anal Bioanal Chem. 2012. PMID: 21877185 Clinical Trial.

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