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Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.
Jenkins CM, Han X, Mancuso DJ, Gross RW. Jenkins CM, et al. Among authors: gross rw. J Biol Chem. 2002 Sep 6;277(36):32807-14. doi: 10.1074/jbc.M202568200. Epub 2002 Jun 27. J Biol Chem. 2002. PMID: 12089145 Free article.
Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition.
Mancuso DJ, Abendschein DR, Jenkins CM, Han X, Saffitz JE, Schuessler RB, Gross RW. Mancuso DJ, et al. Among authors: gross rw. J Biol Chem. 2003 Jun 20;278(25):22231-6. doi: 10.1074/jbc.C300033200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12719436 Free article.
The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling.
Yan W, Jenkins CM, Han X, Mancuso DJ, Sims HF, Yang K, Gross RW. Yan W, et al. Among authors: gross rw. J Biol Chem. 2005 Jul 22;280(29):26669-79. doi: 10.1074/jbc.M502358200. Epub 2005 May 20. J Biol Chem. 2005. PMID: 15908428 Free article.
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW. Mancuso DJ, et al. Among authors: gross rw. J Biol Chem. 2007 Mar 23;282(12):9216-27. doi: 10.1074/jbc.M607307200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213206 Free article.
232 results