Huezo H - Search Results

1

Development of purine-scaffold small molecule inhibitors of Hsp90.

Chiosis G, Lucas B, Huezo H, Solit D, Basso A, Rosen N. Chiosis G, et al. Among authors: huezo h. Curr Cancer Drug Targets. 2003 Oct;3(5):371-6. doi: 10.2174/1568009033481778. Curr Cancer Drug Targets. 2003. PMID: 14529388 Review.

2

Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase.

Chiosis G, Lucas B, Shtil A, Huezo H, Rosen N. Chiosis G, et al. Among authors: huezo h. Bioorg Med Chem. 2002 Nov;10(11):3555-64. doi: 10.1016/s0968-0896(02)00253-5. Bioorg Med Chem. 2002. PMID: 12213470

3

17AAG: low target binding affinity and potent cell activity--finding an explanation.

Chiosis G, Huezo H, Rosen N, Mimnaugh E, Whitesell L, Neckers L. Chiosis G, et al. Among authors: huezo h. Mol Cancer Ther. 2003 Feb;2(2):123-9. Mol Cancer Ther. 2003. PMID: 12589029

4

Synthesis of novel fluorescent probes for the molecular chaperone Hsp90.

Llauger-Bufi L, Felts SJ, Huezo H, Rosen N, Chiosis G. Llauger-Bufi L, et al. Among authors: huezo h. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3975-8. doi: 10.1016/j.bmcl.2003.08.065. Bioorg Med Chem Lett. 2003. PMID: 14592488

5

Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

Vilenchik M, Solit D, Basso A, Huezo H, Lucas B, He H, Rosen N, Spampinato C, Modrich P, Chiosis G. Vilenchik M, et al. Among authors: huezo h. Chem Biol. 2004 Jun;11(6):787-97. doi: 10.1016/j.chembiol.2004.04.008. Chem Biol. 2004. PMID: 15217612

6

Development of a fluorescence polarization assay for the molecular chaperone Hsp90.

Kim J, Felts S, Llauger L, He H, Huezo H, Rosen N, Chiosis G. Kim J, et al. Among authors: huezo h. J Biomol Screen. 2004 Aug;9(5):375-81. doi: 10.1177/1087057104265995. J Biomol Screen. 2004. PMID: 15296636

7

Microtiter cell-based assay for detection of agents that alter cellular levels of Her2 and EGFR.

Huezo H, Vilenchik M, Rosen N, Chiosis G. Huezo H, et al. Chem Biol. 2003 Jul;10(7):629-34. doi: 10.1016/s1074-5521(03)00144-3. Chem Biol. 2003. PMID: 12890536 Free article.

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