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CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.
Ruggeri B, Singh J, Gingrich D, Angeles T, Albom M, Yang S, Chang H, Robinson C, Hunter K, Dobrzanski P, Jones-Bolin S, Pritchard S, Aimone L, Klein-Szanto A, Herbert JM, Bono F, Schaeffer P, Casellas P, Bourie B, Pili R, Isaacs J, Ator M, Hudkins R, Vaught J, Mallamo J, Dionne C. Ruggeri B, et al. Among authors: isaacs j. Cancer Res. 2003 Sep 15;63(18):5978-91. Cancer Res. 2003. PMID: 14522925
Meeting Report: The Sixth International Sam Strober Workshop on Clinical Immune Tolerance.
Stark H, Ho QY, Cross A, Alessandrini A, Bertaina A, Brennan D, Busque S, Demetris A, Devey L, Fruhwirth G, Fuchs E, Friend P, Geissler E, Guillonneau C, Hester J, Isaacs J, Jaeckel E, Kawai T, Lakkis F, Leventhal J, Levings M, Levitsky J, Lombardi G, Martinez-Llordella M, Mathew J, Moreau A, Reinke P, Riella LV, Sachs D, Fueyo AS, Schreeb K, Sykes M, Tang Q, Thomson A, Tree T, Trzonkowski P, Uchida K, Veale J, Weiner J, Wekerle T, Issa F. Stark H, et al. Among authors: isaacs j. Transplantation. 2025 Jan 13. doi: 10.1097/TP.0000000000005311. Online ahead of print. Transplantation. 2025. PMID: 39800883 No abstract available.
Potential Process Control Issues with Vasopressin.
Isaacs JT, Almeter PJ, Hunter AN, Lyman TA, Zapata SP, Henderson BS, Larkin SA, Plymale AR, Long LM, Bossle MN, Bhaktawara SA, Warren MF, Lozier AM, Melson JD, Fraley SR, Relucio EHL, Felix MA, Reynolds JW, Naseman RW, Puerto DA, Lodder RA. Isaacs JT, et al. Contact Context. 2024;2024:10.6084/m9.figshare.27669543. doi: 10.6084/m9.figshare.27669543. Contact Context. 2024. PMID: 39713721 Free PMC article.
Androgen receptor drives polyamine synthesis creating a vulnerability for prostate cancer.
Kumar R, Jonnatan S, Sanin DE, Vakkala V, Kadam A, Kumar S, Dalrymple SL, Zhao L, Foley J, Holbert CE, Nwafor A, Kittane S, Penner E, Apostolova P, Warner S, Dang CV, Toska E, Thompson EA, Isaacs JT, De Marzo AM, Pearce EL, Stewart TM, Casero RA, Denmeade SR, Sena LA. Kumar R, et al. Among authors: isaacs jt. medRxiv [Preprint]. 2024 Dec 13:2024.12.12.24318845. doi: 10.1101/2024.12.12.24318845. medRxiv. 2024. PMID: 39711733 Free PMC article. Preprint.
Relationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Reynolds HR, Page CB, Shaw LJ, Berman DS, Chaitman BR, Picard MH, Kwong RY, Min JK, Leipsic J, Mancini GBJ, Budoff MJ, Hague CJ, Senior R, Szwed H, Bhargava B, Celutkiene J, Gadkari M, Bainey KR, Doerr R, Ramos RB, Ong P, Naik SR, Steg PG, Goetschalckx K, Chow BJW, Scherrer-Crosbie M, Phillips L, Mark DB, Spertus JA, Alexander KP, O'Brien SM, Boden WE, Bangalore S, Stone GW, Maron DJ, Hochman JS; ISCHEMIA Research Group. Reynolds HR, et al. Circ Cardiovasc Interv. 2024 Dec;17(12):e013743. doi: 10.1161/CIRCINTERVENTIONS.123.013743. Epub 2024 Dec 17. Circ Cardiovasc Interv. 2024. PMID: 39689188 Clinical Trial.
Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis.
MacDonald L, Elmesmari A, Somma D, Frew J, Di Mario C, Madhu R, Paoletti A, Simakou T, Hardy OM, Tolusso B, Campobasso D, Perniola S, Gessi M, Gigante MR, Petricca L, Bruno D, Coletto LA, Benvenuto R, Isaacs JD, Filby A, McDonald D, Sim JPX, Jamieson N, Wei K, D'Agostino MA, Millar NL, Milling S, McSharry C, Gremese E, Affleck K, Baker KF, McInnes IB, Otto TD, Korsunsky I, Alivernini S, Kurowska-Stolarska M. MacDonald L, et al. Among authors: isaacs jd. Immunity. 2024 Dec 10;57(12):2843-2862.e12. doi: 10.1016/j.immuni.2024.11.004. Epub 2024 Nov 27. Immunity. 2024. PMID: 39609125 Free article.
1,178 results