Focia PJ - Search Results

1

An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury.

Velentza AV, Wainwright MS, Zasadzki M, Mirzoeva S, Schumacher AM, Haiech J, Focia PJ, Egli M, Watterson DM. Velentza AV, et al. Among authors: focia pj. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3465-70. doi: 10.1016/s0960-894x(03)00733-9. Bioorg Med Chem Lett. 2003. PMID: 14505650

2

Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.

Freymann DM, Wenck MA, Engel JC, Feng J, Focia PJ, Eakin AE, Craig SP. Freymann DM, et al. Among authors: focia pj. Chem Biol. 2000 Dec;7(12):957-68. doi: 10.1016/s1074-5521(00)00045-4. Chem Biol. 2000. PMID: 11137818

3

Structures of ceftazidime and its transition-state analogue in complex with AmpC beta-lactamase: implications for resistance mutations and inhibitor design.

Powers RA, Caselli E, Focia PJ, Prati F, Shoichet BK. Powers RA, et al. Among authors: focia pj. Biochemistry. 2001 Aug 7;40(31):9207-14. doi: 10.1021/bi0109358. Biochemistry. 2001. PMID: 11478888

4

Novel protein and Mg2+ configurations in the Mg2+GDP complex of the SRP GTPase ffh.

Focia PJ, Alam H, Lu T, Ramirez UD, Freymann DM. Focia PJ, et al. Proteins. 2004 Feb 1;54(2):222-30. doi: 10.1002/prot.10598. Proteins. 2004. PMID: 14696184 Free PMC article.

5

Nucleotide-binding flexibility in ultrahigh-resolution structures of the SRP GTPase Ffh.

Ramirez UD, Focia PJ, Freymann DM. Ramirez UD, et al. Among authors: focia pj. Acta Crystallogr D Biol Crystallogr. 2008 Oct;64(Pt 10):1043-53. doi: 10.1107/S090744490802444X. Epub 2008 Sep 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18931411 Free PMC article.

6

Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.

Shim AH, Liu H, Focia PJ, Chen X, Lin PC, He X. Shim AH, et al. Among authors: focia pj. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11307-12. doi: 10.1073/pnas.1000806107. Epub 2010 Jun 2. Proc Natl Acad Sci U S A. 2010. PMID: 20534510 Free PMC article.

7

Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh.

Ramirez UD, Minasov G, Focia PJ, Stroud RM, Walter P, Kuhn P, Freymann DM. Ramirez UD, et al. Among authors: focia pj. J Mol Biol. 2002 Jul 19;320(4):783-99. doi: 10.1016/s0022-2836(02)00476-x. J Mol Biol. 2002. PMID: 12095255 Free PMC article.

8

Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.

Chen X, Liu H, Focia PJ, Shim AH, He X. Chen X, et al. Among authors: focia pj. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18267-72. doi: 10.1073/pnas.0807762105. Epub 2008 Nov 18. Proc Natl Acad Sci U S A. 2008. PMID: 19017797 Free PMC article.

9

Homophilic adhesion mechanism of neurofascin, a member of the L1 family of neural cell adhesion molecules.

Liu H, Focia PJ, He X. Liu H, et al. Among authors: focia pj. J Biol Chem. 2011 Jan 7;286(1):797-805. doi: 10.1074/jbc.M110.180281. Epub 2010 Nov 3. J Biol Chem. 2011. PMID: 21047790 Free PMC article.

10

Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.

Chen X, Liu H, Shim AH, Focia PJ, He X. Chen X, et al. Among authors: focia pj. Nat Struct Mol Biol. 2008 Jan;15(1):50-6. doi: 10.1038/nsmb1350. Epub 2007 Dec 16. Nat Struct Mol Biol. 2008. PMID: 18084303 Free PMC article.

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