Manser T - Search Results

1

Somatic recombination of heavy chain variable region transgenes with the endogenous immunoglobulin heavy chain locus in mice.

Giusti AM, Coffee R, Manser T. Giusti AM, et al. Among authors: manser t. Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10321-5. doi: 10.1073/pnas.89.21.10321. Proc Natl Acad Sci U S A. 1992. PMID: 1438216 Free PMC article.

2

Somatic generation of hybrid antibody H chain genes in transgenic mice via interchromosomal gene conversion.

Giusti AM, Manser T. Giusti AM, et al. Among authors: manser t. J Exp Med. 1994 Jan 1;179(1):235-48. doi: 10.1084/jem.179.1.235. J Exp Med. 1994. PMID: 8270869 Free PMC article.

3

Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation.

Giusti AM, Manser T. Giusti AM, et al. Among authors: manser t. J Exp Med. 1993 Mar 1;177(3):797-809. doi: 10.1084/jem.177.3.797. J Exp Med. 1993. PMID: 8436910 Free PMC article.

4

Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches.

Tumas-Brundage K, Vora KA, Giusti AM, Manser T. Tumas-Brundage K, et al. Among authors: manser t. Semin Immunol. 1996 Jun;8(3):141-50. doi: 10.1006/smim.1996.0018. Semin Immunol. 1996. PMID: 8738913 Review.

5

The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.

Manser T, Tumas-Brundage KM, Casson LP, Giusti AM, Hande S, Notidis E, Vora KA. Manser T, et al. Immunol Rev. 1998 Apr;162:183-96. doi: 10.1111/j.1600-065x.1998.tb01441.x. Immunol Rev. 1998. PMID: 9602364 Review.

6

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus.

Tumas-Brundage K, Manser T. Tumas-Brundage K, et al. Among authors: manser t. J Exp Med. 1997 Jan 20;185(2):239-50. doi: 10.1084/jem.185.2.239. J Exp Med. 1997. PMID: 9016873 Free PMC article.

7

Regulation of the immune response to peptide antigens: differential induction of immediate-type hypersensitivity and T cell proliferation due to changes in either peptide structure or major histocompatibility complex haplotype.

Soloway P, Fish S, Passmore H, Gefter M, Coffee R, Manser T. Soloway P, et al. Among authors: manser t. J Exp Med. 1991 Oct 1;174(4):847-58. doi: 10.1084/jem.174.4.847. J Exp Med. 1991. PMID: 1919438 Free PMC article.

8

Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates.

Manser T, Gefter ML. Manser T, et al. Proc Natl Acad Sci U S A. 1984 Apr;81(8):2470-4. doi: 10.1073/pnas.81.8.2470. Proc Natl Acad Sci U S A. 1984. PMID: 6425832 Free PMC article.

9

Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation.

Tumas-Brundage KM, Vora KA, Manser T. Tumas-Brundage KM, et al. Among authors: manser t. Mol Immunol. 1997 Apr;34(5):367-78. doi: 10.1016/s0161-5890(97)00065-5. Mol Immunol. 1997. PMID: 9293770

10

Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation.

Vora KA, Manser T. Vora KA, et al. Among authors: manser t. J Exp Med. 1995 Jan 1;181(1):271-81. doi: 10.1084/jem.181.1.271. J Exp Med. 1995. PMID: 7807007 Free PMC article.

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