Greig NH - Search Results

1

The long-acting cholinesterase inhibitor heptyl-physostigmine attenuates the scopolamine-induced learning impairment of rats in a 14-unit T-maze.

Iijima S, Greig NH, Garofalo P, Spangler EL, Heller B, Brossi A, Ingram DK. Iijima S, et al. Among authors: greig nh. Neurosci Lett. 1992 Sep 14;144(1-2):79-83. doi: 10.1016/0304-3940(92)90720-r. Neurosci Lett. 1992. PMID: 1436716

2

Clinical pharmacokinetics of physostigmine in patients with Alzheimer's disease.

Asthana S, Greig NH, Hegedus L, Holloway HH, Raffaele KC, Schapiro MB, Soncrant TT. Asthana S, et al. Among authors: greig nh. Clin Pharmacol Ther. 1995 Sep;58(3):299-309. doi: 10.1016/0009-9236(95)90246-5. Clin Pharmacol Ther. 1995. PMID: 7554703 Clinical Trial.

3

Maze learning in aged rats is enhanced by phenserine, a novel anticholinesterase.

Ikari H, Spangler EL, Greig NH, Pei XF, Brossi A, Speer D, Patel N, Ingram DK. Ikari H, et al. Among authors: greig nh. Neuroreport. 1995 Feb 15;6(3):481-4. doi: 10.1097/00001756-199502000-00019. Neuroreport. 1995. PMID: 7766848

4

Phenserine: a physostigmine derivative that is a long-acting inhibitor of cholinesterase and demonstrates a wide dose range for attenuating a scopolamine-induced learning impairment of rats in a 14-unit T-maze.

Iijima S, Greig NH, Garofalo P, Spangler EL, Heller B, Brossi A, Ingram DK. Iijima S, et al. Among authors: greig nh. Psychopharmacology (Berl). 1993;112(4):415-20. doi: 10.1007/BF02244888. Psychopharmacology (Berl). 1993. PMID: 7871051

5

Phenserine and ring C hetero-analogues: drug candidates for the treatment of Alzheimer's disease.

Greig NH, Pei XF, Soncrant TT, Ingram DK, Brossi A. Greig NH, et al. Med Res Rev. 1995 Jan;15(1):3-31. doi: 10.1002/med.2610150103. Med Res Rev. 1995. PMID: 7898167 Review. No abstract available.

6

Rodent models of memory dysfunction in Alzheimer's disease and normal aging: moving beyond the cholinergic hypothesis.

Ingram DK, Spangler EL, Iijima S, Ikari H, Kuo H, Greig NH, London ED. Ingram DK, et al. Among authors: greig nh. Life Sci. 1994;55(25-26):2037-49. doi: 10.1016/0024-3205(94)00384-x. Life Sci. 1994. PMID: 7997063 Review.

7

New pharmacological strategies for cognitive enhancement using a rat model of age-related memory impairment.

Ingram DK, Spangler EL, Iijima S, Kuo H, Bresnahan EL, Greig NH, London ED. Ingram DK, et al. Among authors: greig nh. Ann N Y Acad Sci. 1994 Jun 30;717:16-32. doi: 10.1111/j.1749-6632.1994.tb12070.x. Ann N Y Acad Sci. 1994. PMID: 8030831 Review.

8

Cognitive enhancement. New strategies for stimulating cholinergic, glutamatergic, and nitric oxide systems.

Ingram DK, Shimada A, Spangler EL, Ikari H, Hengemihle J, Kuo H, Greig N. Ingram DK, et al. Ann N Y Acad Sci. 1996 Jun 15;786:348-61. doi: 10.1111/j.1749-6632.1996.tb39076.x. Ann N Y Acad Sci. 1996. PMID: 8687034 Review.

9

Total syntheses and anticholinesterase activities of (3aS)-N(8)-norphysostigmine, (3aS)-N(8)-norphenserine, their antipodal isomers, and other N(8)-substituted analogues.

Yu QS, Pei XF, Holloway HW, Greig NH, Brossi A. Yu QS, et al. Among authors: greig nh. J Med Chem. 1997 Aug 29;40(18):2895-901. doi: 10.1021/jm970210v. J Med Chem. 1997. PMID: 9288171

10

Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N-methyl-D-aspartate receptor.

Patel N, Spangler EL, Greig NH, Yu QS, Ingram DK, Meyer RC. Patel N, et al. Among authors: greig nh. Neuroreport. 1998 Jan 5;9(1):171-6. doi: 10.1097/00001756-199801050-00035. Neuroreport. 1998. PMID: 9592071

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