Margolis B - Search Results

1

High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains.

Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J. Margolis B, et al. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8894-8. doi: 10.1073/pnas.89.19.8894. Proc Natl Acad Sci U S A. 1992. PMID: 1409582 Free PMC article.

2

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors.

Hu P, Margolis B, Skolnik EY, Lammers R, Ullrich A, Schlessinger J. Hu P, et al. Among authors: margolis b. Mol Cell Biol. 1992 Mar;12(3):981-90. doi: 10.1128/mcb.12.3.981-990.1992. Mol Cell Biol. 1992. PMID: 1372091 Free PMC article.

We recently cloned the 85-kDa subunit of PI 3-kinase (p85) from a lambda gt11 expression library, using the tyrosine-phosphorylated carboxy terminus of the epidermal growth factor (EGF) receptor as a probe (E. Y. Skolnik, B. Margolis, M. Mohammadi, E. Lowenstein, R. …

We recently cloned the 85-kDa subunit of PI 3-kinase (p85) from a lambda gt11 expression library, using the tyrosine-phosphorylated carboxy …

3

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma.

Rotin D, Margolis B, Mohammadi M, Daly RJ, Daum G, Li N, Fischer EH, Burgess WH, Ullrich A, Schlessinger J. Rotin D, et al. Among authors: margolis b. EMBO J. 1992 Feb;11(2):559-67. doi: 10.1002/j.1460-2075.1992.tb05087.x. EMBO J. 1992. PMID: 1537335 Free PMC article.

4

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.

Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schlessinger J. Skolnik EY, et al. Among authors: margolis b. Cell. 1991 Apr 5;65(1):83-90. doi: 10.1016/0092-8674(91)90410-z. Cell. 1991. PMID: 1849461 Free article.

5

Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain.

Dikic I, Batzer AG, Blaikie P, Obermeier A, Ullrich A, Schlessinger J, Margolis B. Dikic I, et al. Among authors: margolis b. J Biol Chem. 1995 Jun 23;270(25):15125-9. doi: 10.1074/jbc.270.25.15125. J Biol Chem. 1995. PMID: 7541035 Free article.

6

Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.

Li N, Schlessinger J, Margolis B. Li N, et al. Among authors: margolis b. Oncogene. 1994 Dec;9(12):3457-65. Oncogene. 1994. PMID: 7970705

7

Use of tyrosine-phosphorylated proteins to screen bacterial expression libraries for SH2 domains.

Margolis B, Skolnik EY, Schlessinger J. Margolis B, et al. Methods Enzymol. 1995;255:360-9. doi: 10.1016/s0076-6879(95)55038-0. Methods Enzymol. 1995. PMID: 8524121 No abstract available.

8

Presence of SH2 domains of phospholipase C gamma 1 enhances substrate phosphorylation by increasing the affinity toward the epidermal growth factor receptor.

Rotin D, Honegger AM, Margolis BL, Ullrich A, Schlessinger J. Rotin D, et al. Among authors: margolis bl. J Biol Chem. 1992 May 15;267(14):9678-83. J Biol Chem. 1992. PMID: 1315766 Free article.

9

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D, Schlessinger J. Lowenstein EJ, et al. Among authors: margolis b. Cell. 1992 Aug 7;70(3):431-42. doi: 10.1016/0092-8674(92)90167-b. Cell. 1992. PMID: 1322798 Free article.

10

Role of SH2-containing proteins in cellular signaling by receptor tyrosine kinases.

Schlessinger J, Mohammadi M, Margolis B, Ullrich A. Schlessinger J, et al. Among authors: margolis b. Cold Spring Harb Symp Quant Biol. 1992;57:67-74. doi: 10.1101/sqb.1992.057.01.009. Cold Spring Harb Symp Quant Biol. 1992. PMID: 1339705 No abstract available.

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