Cortopassi G - Search Results

1

Deleterious mitochondrial DNA mutations accumulate in aging human tissues.

Arnheim N, Cortopassi G. Arnheim N, et al. Among authors: cortopassi g. Mutat Res. 1992 Sep;275(3-6):157-67. doi: 10.1016/0921-8734(92)90020-p. Mutat Res. 1992. PMID: 1383758 Review.

2

Using the polymerase chain reaction to estimate mutation frequencies and rates in human cells.

Cortopassi GA, Arnheim N. Cortopassi GA, et al. Mutat Res. 1992 Sep;277(3):239-49. doi: 10.1016/0165-1110(92)90046-c. Mutat Res. 1992. PMID: 1381052 Review.

3

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.

Cortopassi GA, Shibata D, Soong NW, Arnheim N. Cortopassi GA, et al. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7370-4. doi: 10.1073/pnas.89.16.7370. Proc Natl Acad Sci U S A. 1992. PMID: 1502147 Free PMC article.

4

Detection of a specific mitochondrial DNA deletion in tissues of older humans.

Cortopassi GA, Arnheim N. Cortopassi GA, et al. Nucleic Acids Res. 1990 Dec 11;18(23):6927-33. doi: 10.1093/nar/18.23.6927. Nucleic Acids Res. 1990. PMID: 2263455 Free PMC article.

5

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain.

Soong NW, Hinton DR, Cortopassi G, Arnheim N. Soong NW, et al. Among authors: cortopassi g. Nat Genet. 1992 Dec;2(4):318-23. doi: 10.1038/ng1292-318. Nat Genet. 1992. PMID: 1303287

6

A simple method for site-directed mutagenesis using the polymerase chain reaction.

Hemsley A, Arnheim N, Toney MD, Cortopassi G, Galas DJ. Hemsley A, et al. Among authors: cortopassi g. Nucleic Acids Res. 1989 Aug 25;17(16):6545-51. doi: 10.1093/nar/17.16.6545. Nucleic Acids Res. 1989. PMID: 2674899 Free PMC article.

7

The mutation rate of the human mtDNA deletion mtDNA4977.

Shenkar R, Navidi W, Tavaré S, Dang MH, Chomyn A, Attardi G, Cortopassi G, Arnheim N. Shenkar R, et al. Among authors: cortopassi g. Am J Hum Genet. 1996 Oct;59(4):772-80. Am J Hum Genet. 1996. PMID: 8808591 Free PMC article.

8

Genotypic selection of mitochondrial and oncogenic mutations in human tissue suggests mechanisms of age-related pathophysiology.

Cortopassi G, Liu Y. Cortopassi G, et al. Mutat Res. 1995 Oct;338(1-6):151-9. doi: 10.1016/0921-8734(95)00020-7. Mutat Res. 1995. PMID: 7565870 Review.

9

The rate of mitochondrial mutagenesis is faster in mice than humans.

Wang E, Wong A, Cortopassi G. Wang E, et al. Among authors: cortopassi g. Mutat Res. 1997 Jul 3;377(2):157-66. doi: 10.1016/s0027-5107(97)00091-2. Mutat Res. 1997. PMID: 9247611

10

A low dose of ethidium bromide leads to an increase of total mitochondrial DNA while higher concentrations induce the mtDNA 4997 deletion in a human neuronal cell line.

von Wurmb-Schwark N, Cavelier L, Cortopassi GA. von Wurmb-Schwark N, et al. Among authors: cortopassi ga. Mutat Res. 2006 Apr 11;596(1-2):57-63. doi: 10.1016/j.mrfmmm.2005.12.003. Epub 2006 Feb 20. Mutat Res. 2006. PMID: 16488450

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