Doyle K - Search Results

1

Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities.

Markovich KM, Tantishaiyakul V, Hamada A, Miller DD, Romstedt KJ, Shams G, Shin Y, Fraundorfer PF, Doyle K, Feller DR. Markovich KM, et al. Among authors: doyle k. J Med Chem. 1992 Feb 7;35(3):466-79. doi: 10.1021/jm00081a007. J Med Chem. 1992. PMID: 1346651

2

Pharmacologic antagonism of thromboxane A2 receptors by trimetoquinol analogs in vitro and in vivo.

Shin Y, Romstedt KJ, Doyle K, Harrold MW, Gerhardt MA, Miller DD, Patil PN, Feller DR. Shin Y, et al. Among authors: doyle k. Chirality. 1991;3(2):112-7. doi: 10.1002/chir.530030206. Chirality. 1991. PMID: 1830752

3

Halogen-substituted trimetoquinol analogs as thromboxane A2 receptor antagonists in platelets and aorta.

Romstedt KJ, Shin Y, Shams G, Doyle K, Tantishaiyakul V, Clark MT, Adejare A, Hamada A, Miller DD, Feller DR. Romstedt KJ, et al. Among authors: doyle k. Biochem Pharmacol. 1993 Dec 3;46(11):2051-9. doi: 10.1016/0006-2952(93)90647-f. Biochem Pharmacol. 1993. PMID: 8267653

4

The mechanism of the neurotoxic effects of spermidine.

Doyle KM, Shaw GG. Doyle KM, et al. Biochem Soc Trans. 1994 Nov;22(4):386S. doi: 10.1042/bst022386s. Biochem Soc Trans. 1994. PMID: 7698409 No abstract available.

5

Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo.

Doyle KM, Shaw GG. Doyle KM, et al. Br J Pharmacol. 1996 Apr;117(8):1803-8. doi: 10.1111/j.1476-5381.1996.tb15358.x. Br J Pharmacol. 1996. PMID: 8732295 Free PMC article.

6

Investigation of the actions and antagonist activity of some polyamine analogues in vivo.

Doyle KM, Shaw GG. Doyle KM, et al. Br J Pharmacol. 1998 May;124(2):386-90. doi: 10.1038/sj.bjp.0701839. Br J Pharmacol. 1998. PMID: 9641557 Free PMC article.

7

Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation.

Bailey D, Kirby BP, Atkinson J, Fixon-Owoo S, Henman MC, Shaw GG, Doyle KM. Bailey D, et al. Pharmacol Biochem Behav. 2015 Jun;133:57-64. doi: 10.1016/j.pbb.2015.03.014. Epub 2015 Mar 28. Pharmacol Biochem Behav. 2015. PMID: 25824983

8

Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.

Doyle KM, Kirby BP, Murphy D, Shaw GG. Doyle KM, et al. Neurosci Lett. 2005 Jun 3;380(3):247-51. doi: 10.1016/j.neulet.2005.01.052. Epub 2005 Feb 1. Neurosci Lett. 2005. PMID: 15862895

9

The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice.

Li J, Henman MC, Doyle KM, Strbian D, Kirby BP, Tatlisumak T, Shaw GG. Li J, et al. Brain Res. 2004 Dec 10;1029(1):84-92. doi: 10.1016/j.brainres.2004.09.037. Brain Res. 2004. PMID: 15533319

10

The pre-ischaemic neuroprotective effects of N1-dansyl-spermine in a transient focal cerebral ischaemia model in mice.

Li J, Henman MC, Tatlisumak T, Shaw GG, Doyle KM. Li J, et al. Brain Res. 2005 Sep 7;1055(1-2):180-5. doi: 10.1016/j.brainres.2005.07.023. Brain Res. 2005. PMID: 16095573

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