Backer JM - Search Results

1

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.

Myers MG Jr, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF. Myers MG Jr, et al. Among authors: backer jm. Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10350-4. doi: 10.1073/pnas.89.21.10350. Proc Natl Acad Sci U S A. 1992. PMID: 1332046 Free PMC article.

2

Mutations in the juxtamembrane region of the insulin receptor impair activation of phosphatidylinositol 3-kinase by insulin.

Kapeller R, Chen KS, Yoakim M, Schaffhausen BS, Backer J, White MF, Cantley LC, Ruderman NB. Kapeller R, et al. Mol Endocrinol. 1991 Jun;5(6):769-77. doi: 10.1210/mend-5-6-769. Mol Endocrinol. 1991. PMID: 1656240

3

Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.

Backer JM, Schroeder GG, Kahn CR, Myers MG Jr, Wilden PA, Cahill DA, White MF. Backer JM, et al. J Biol Chem. 1992 Jan 15;267(2):1367-74. J Biol Chem. 1992. PMID: 1309768 Free article.

4

Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

Backer JM, Myers MG Jr, Shoelson SE, Chin DJ, Sun XJ, Miralpeix M, Hu P, Margolis B, Skolnik EY, Schlessinger J, et al. Backer JM, et al. EMBO J. 1992 Sep;11(9):3469-79. doi: 10.1002/j.1460-2075.1992.tb05426.x. EMBO J. 1992. PMID: 1380456 Free PMC article.

5

Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells.

Miralpeix M, Sun XJ, Backer JM, Myers MG Jr, Araki E, White MF. Miralpeix M, et al. Among authors: backer jm. Biochemistry. 1992 Sep 22;31(37):9031-9. doi: 10.1021/bi00152a046. Biochemistry. 1992. PMID: 1382584

6

Expression and function of IRS-1 in insulin signal transmission.

Sun XJ, Miralpeix M, Myers MG Jr, Glasheen EM, Backer JM, Kahn CR, White MF. Sun XJ, et al. Among authors: backer jm. J Biol Chem. 1992 Nov 5;267(31):22662-72. J Biol Chem. 1992. PMID: 1385403 Free article.

7

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF. Sun XJ, et al. Among authors: backer jm. Nature. 1991 Jul 4;352(6330):73-7. doi: 10.1038/352073a0. Nature. 1991. PMID: 1648180

8

The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth.

Wilden PA, Backer JM, Kahn CR, Cahill DA, Schroeder GJ, White MF. Wilden PA, et al. Among authors: backer jm. Proc Natl Acad Sci U S A. 1990 May;87(9):3358-62. doi: 10.1073/pnas.87.9.3358. Proc Natl Acad Sci U S A. 1990. PMID: 2159147 Free PMC article.

9

Tyrosine phosphorylation of the insulin receptor is not required for receptor internalization: studies in 2,4-dinitrophenol-treated cells.

Backer JM, Kahn CR, White MF. Backer JM, et al. Proc Natl Acad Sci U S A. 1989 May;86(9):3209-13. doi: 10.1073/pnas.86.9.3209. Proc Natl Acad Sci U S A. 1989. PMID: 2470095 Free PMC article.

10

Common and distinct elements in insulin and PDGF signaling.

Myers MG Jr, Cheatham B, Fisher TL, Jachna BR, Kahn CR, Backer JM, White MF. Myers MG Jr, et al. Among authors: backer jm. Ann N Y Acad Sci. 1995 Sep 7;766:369-87. doi: 10.1111/j.1749-6632.1995.tb26687.x. Ann N Y Acad Sci. 1995. PMID: 7486683

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