Gambino J - Search Results

1

Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases.

Gambino J, Focher F, Hildebrand C, Maga G, Noonan T, Spadari S, Wright G. Gambino J, et al. J Med Chem. 1992 Aug 7;35(16):2979-83. doi: 10.1021/jm00094a007. J Med Chem. 1992. PMID: 1323680

2

Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.

Manikowski A, Verri A, Lossani A, Gebhardt BM, Gambino J, Focher F, Spadari S, Wright GE. Manikowski A, et al. Among authors: gambino j. J Med Chem. 2005 Jun 2;48(11):3919-29. doi: 10.1021/jm049059x. J Med Chem. 2005. PMID: 15916444 Free PMC article.

3

Quantitative structure-activity relationships of 6-anilinouracils as inhibitors of Bacillus subtilis DNA polymerase III.

Wright GE, Gambino JJ. Wright GE, et al. Among authors: gambino jj. J Med Chem. 1984 Feb;27(2):181-5. doi: 10.1021/jm00368a013. J Med Chem. 1984. PMID: 6420570

4

6-Anilinouracil-based inhibitors of Bacillus subtilis DNA polymerase III: antipolymerase and antimicrobial structure-activity relationships based on substitution at uracil N3.

Tarantino PM Jr, Zhi C, Gambino JJ, Wright GE, Brown NC. Tarantino PM Jr, et al. Among authors: gambino jj. J Med Chem. 1999 Jun 3;42(11):2035-40. doi: 10.1021/jm980693i. J Med Chem. 1999. PMID: 10354411

5

Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases.

Hildebrand C, Sandoli D, Focher F, Gambino J, Ciarrocchi G, Spadari S, Wright G. Hildebrand C, et al. Among authors: gambino j. J Med Chem. 1990 Jan;33(1):203-6. doi: 10.1021/jm00163a033. J Med Chem. 1990. PMID: 2153203

6

Synthesis, properties, and pharmacokinetic studies of N2-phenylguanine derivatives as inhibitors of herpes simplex virus thymidine kinases.

Xu H, Maga G, Focher F, Smith ER, Spadari S, Gambino J, Wright GE. Xu H, et al. Among authors: gambino j. J Med Chem. 1995 Jan 6;38(1):49-57. doi: 10.1021/jm00001a010. J Med Chem. 1995. PMID: 7837239

7

Active site directed inhibitors of replication-specific bacterial DNA polymerases.

Wright GE, Brown NC, Xu WC, Long ZY, Zhi C, Gambino JJ, Barnes MH, Butler MM. Wright GE, et al. Among authors: gambino jj. Bioorg Med Chem Lett. 2005 Feb 1;15(3):729-32. doi: 10.1016/j.bmcl.2004.11.016. Bioorg Med Chem Lett. 2005. PMID: 15664846

8

Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.

Focher F, Lossani A, Verri A, Spadari S, Maioli A, Gambino JJ, Wright GE, Eberle R, Black DH, Medveczky P, Medveczky M, Shugar D. Focher F, et al. Among authors: gambino jj. Antimicrob Agents Chemother. 2007 Jun;51(6):2028-34. doi: 10.1128/AAC.01284-06. Epub 2007 Apr 16. Antimicrob Agents Chemother. 2007. PMID: 17438061 Free PMC article.

9

Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth.

Zhi C, Long ZY, Gambino J, Xu WC, Brown NC, Barnes M, Butler M, LaMarr W, Wright GE. Zhi C, et al. Among authors: gambino j. J Med Chem. 2003 Jun 19;46(13):2731-9. doi: 10.1021/jm020591z. J Med Chem. 2003. PMID: 12801236

10

N²-Phenyl-9-(hydroxyalkyl)guanines and related compounds are substrates for Herpes simplex virus thymidine kinases.

Lossani A, Savi L, Manikowski A, Maioli A, Gambino J, Focher F, Spadari S, Wright GE. Lossani A, et al. Among authors: gambino j. J Mol Biochem. 2012;1(1):21-25. J Mol Biochem. 2012. PMID: 24734222 Free PMC article.

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