De Clercq E - Search Results

1

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.

Neyts J, Balzarini J, Naesens L, De Clercq E. Neyts J, et al. Among authors: de clercq e. J Med Virol. 1992 May;37(1):67-71. doi: 10.1002/jmv.1890370112. J Med Virol. 1992. PMID: 1320099

2

Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate.

Neyts J, Snoeck R, Schols D, Balzarini J, Esko JD, Van Schepdael A, De Clercq E. Neyts J, et al. Among authors: de clercq e. Virology. 1992 Jul;189(1):48-58. doi: 10.1016/0042-6822(92)90680-n. Virology. 1992. PMID: 1376540

3

Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Clin Chem. 1992 Apr;38(4):480-5. Clin Chem. 1992. PMID: 1568310

4

Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.

Snoeck R, Schols D, Andrei G, Neyts J, De Clercq E. Snoeck R, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):1-9. doi: 10.1016/0166-3542(91)90053-t. Antiviral Res. 1991. PMID: 1663725

5

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

Neyts J, Snoeck R, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):41-52. doi: 10.1016/0166-3542(91)90057-x. Antiviral Res. 1991. PMID: 1663729

6

Single-dose administration of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the prophylaxis of retrovirus infection in vivo.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):53-64. doi: 10.1016/0166-3542(91)90058-y. Antiviral Res. 1991. PMID: 1776876

7

5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. J Biol Chem. 1991 May 15;266(14):8686-9. J Biol Chem. 1991. PMID: 1851154 Free article.

8

Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).

Neyts J, Snoeck R, Schols D, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Virology. 1990 Nov;179(1):41-50. doi: 10.1016/0042-6822(90)90271-r. Virology. 1990. PMID: 2171213

9

Inhibitory effects of 9-(2-phosphonylmethoxyethyl)adenine and 3'-azido-2',3'-dideoxythymidine on tumor development in mice inoculated intracerebrally with Moloney murine sarcoma virus.

Balzarini J, Sobis H, Naesens L, Vandeputte M, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Int J Cancer. 1990 Mar 15;45(3):486-9. doi: 10.1002/ijc.2910450319. Int J Cancer. 1990. PMID: 2307539

10

Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered.

Balzarini J, Naesens L, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Int J Cancer. 1990 Aug 15;46(2):337-40. doi: 10.1002/ijc.2910460233. Int J Cancer. 1990. PMID: 2384280

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